Table 1:

Molecular diagnoses for tumors with both imaging and methylation profiles available (n = 56)a

PBL/ETNo.Non-ETNo.
PBL27dGBM_G348
bCNS_NB_FOXR23dGBM_MYCN5
bETMR1dDMG_K272
bHGNET_MN11dGBM_MID2
bMB_WNT1EP_RELA2
bCNS ET, NOS1
cATRT_SHH2
cATRT_MYC1
Total3719
  • Note:—CNS_NB_FOXR2 indicates CNS neuroblastoma with FOXR2 activation; HGNET_MN1, CNS high-grade neuroepithelial tumor with MN1 alteration; MB_WNT: medulloblastoma with wingless (Wnt) activation; ATRT_SHH, atypical teratoid/rhabdoid tumor with sonic hedgehog (shh) activation; ATRT_MYC, atypical teratoid/rhabdoid tumor, subclass MYC; GBM_G34, glioblastoma, Isocitrate dehydrogenase (IDH) wild-type, H3.3 G34 mutant; GBM_MYCN, glioblastoma, IDH wild-type, subclass MYCN; DMG_K27, diffuse midline glioma H3K27M mutant; GBM-MID, glioblastoma, IDH wild-type, subclass midline; EP-RELA, ependymoma with positive RELA fusion.

  • a For further analysis, the following have been combined into single groups:

  • b As ET, other.

  • c As ATRT.

  • d As HGG.