Table 2:

Ketone body concentrations as measured by MR spectroscopy before and after treatment with a ketogenic diet in both the lesion and contralateral braina

Baseline (IU)No.Week 8 (IU)No.P Value
Ace
    Contralateral brain0.04 ± 0.0150.16 ± 0.049.004b
    Lesion0.06 ± 0.0340.27 ± 0.069.005b
bHB
    Contralateral brain0.09 ± 0.0620.28 ± 0.086.12
    Lesion0.07 ± 0.0710.79 ± 0.325.046c
AcAc
    Contralateral brain0.07 ± 0.0430.06 ± 0.033.76
    Lesion0.03 ± 0.0310.02 ± 0.021.72
  • a P value was computed using paired t tests; No. indicates number of spectra in which the metabolite was fitted according to defined criteria. Errors are provided as standard error of the mean. Data are means unless otherwise indicated.

  • b P ≤ .008 (Bonferroni-adjusted threshold).

  • c P ≤ .05.