Molecular diagnoses for tumors with both imaging and methylation profiles available (n = 56)a
| PBL/ET | No. | Non-ET | No. |
|---|---|---|---|
| PBL | 27 | GBM_G34d | 8 |
| CNS_NB_FOXR2b | 3 | GBM_MYCNd | 5 |
| ETMRb | 1 | DMG_K27d | 2 |
| HGNET_MN1b | 1 | GBM_MIDd | 2 |
| MB_WNTb | 1 | EP_RELA | 2 |
| CNS ET, NOSb | 1 | ||
| ATRT_SHHc | 2 | ||
| ATRT_MYCc | 1 | ||
| Total | 37 | 19 |
Note:—CNS_NB_FOXR2 indicates CNS neuroblastoma with FOXR2 activation; HGNET_MN1, CNS high-grade neuroepithelial tumor with MN1 alteration; MB_WNT: medulloblastoma with wingless (Wnt) activation; ATRT_SHH, atypical teratoid/rhabdoid tumor with sonic hedgehog (shh) activation; ATRT_MYC, atypical teratoid/rhabdoid tumor, subclass MYC; GBM_G34, glioblastoma, Isocitrate dehydrogenase (IDH) wild-type, H3.3 G34 mutant; GBM_MYCN, glioblastoma, IDH wild-type, subclass MYCN; DMG_K27, diffuse midline glioma H3K27M mutant; GBM-MID, glioblastoma, IDH wild-type, subclass midline; EP-RELA, ependymoma with positive RELA fusion.
↵a For further analysis, the following have been combined into single groups:
↵b As ET, other.
↵c As ATRT.
↵d As HGG.