Demographics | (No.) (%) |
---|---|
Age (mean) (SD) (yr) | 49.2 (10.6) |
Male sex | 6 (60%) |
WHO grade | |
III | 7 (70%) |
IV | 3 (30%) |
Extent of resection | |
Biopsy | 2 (20%) |
Subtotal | 3 (30%) |
Gross total | 5 (50%) |
IDH1/2 mutational status | |
IDH wild-type | 4 (40%) |
IDH mutant | 6 (60%) |
MGMT promoter methylation status | |
Unmethylated | 4 (40%) |
Methylated | 4 (40%) |
Unknown | 2 (20%) |
Concurrent TMZ (median) (range) (% completed) | 100% (80%–100%) |
Adjuvant TMZ (median) (range) (No. of cycles) | 6 (6–12) |
Note:—IDH indicates isocitrate dehydrogenase; MGMT, O6-methylguanine-DNA methyltransferase; TMZ, temozolomide.