Table 2:

Global differences in the network properties between the patients with CLN3 and the control subjects, with age and sex used as covariates

Network Property	CLN3^a		Control Subjects^a	P
Network Property	First Acquisition	Second Acquisition	Control Subjects^a	CLN3 First Acquisition vs. Control Subjects	CLN3 Second Acquisition vs. Control Subjects
Betweenness centrality	288 ± 22	294 ± 17	278 ± 11	.084	.008
Characteristic path length	0.118 ± 0.062	0.130 ± 0.073	0.074 ± 0.014	.003^{^b}	.003^{^b}
Clustering coefficient	5.27 ± 1.57	5.32 ± 2.12	6.45 ± 0.77	.011	.017
Degree	25.9 ± 4.6	25.3 ± 5.0	29.5 ± 1.79	.003^{^b}	.002^{^b}
Global efficiency	22.6 ± 8.6	22.8 ± 11.6	28.5 ± 4.5	.014	.030
Small-worldness	5.03 ± 0.85	5.24 ± 1.19	5.78 ± 0.80	.009	.126
Strength	511 ± 191	506 ± 255	645 ± 105	.012	.020

a Data are mean± standard deviation.
↵b Indicates significant differences after the Bonferroni correction for multiple comparisons.