Table 3:

Hopkins criteria scores for head and neck cancersa

Hopkins Criteria ScorebLesion FDG UptakeTherapy Response
1Focal uptake less than IJVCMR
2Focal uptake greater than IJV, but less than liverLikely CMR
3Diffuse uptake greater than IJV and liverLikely posttreatment inflammation
4Focal uptake greater than liverLikely residual tumor
5Focal uptake markedly greater than liverResidual tumor
  • Note:—IJV indicates internal jugular vein.

  • a Adapted from Ref. 16.

  • b Five-point scale Hopkins criteria scores used to classify head and neck cancer response after treatment; new lesions are considered to be PD.