Baseline and hemodynamic characteristics for each group
| Stable Aneurysms | Growing Aneurysms: Baseline | Grown Aneurysms: Follow-Up Imaging | |
|---|---|---|---|
| No. | 81 | 56 | 56 |
| Sex | b | ||
| Male | 11 (14%) | 7 (12%) | |
| Female | 53 (65%) | 48 (86%) | |
| Unknown | 17 (21%) | 1 (2%) | |
| Artery (%) | |||
| ACA | 5 (6%) | 1 (2%) | |
| AcomA | 8 (10%) | 8 (14%) | |
| ICA | 37 (46%) | 18 (32%) | |
| MCA | 16 (20%) | 19 (34%) | |
| PcomA | 12 (15%) | 3 (5%) | |
| Posterior circulation | 3 (3%) | 7 (13%) | |
| Previous SAH = yes (%) | 2 (2%) | 14 (25%)a | |
| Configuration = lateral (%) | 33 (41%) | 18 (32%) | |
| Age (mean) (SD) (yr) | 59 (18) | 55 (14) | 59 (13) |
| PHASES (mean) (SD) | 3 (2) | 4 (3)c | 5 (3)a |
| Without hypertension and population | 3 (3) | 4 (3) | 5 (3)c |
| ELAPSS (mean) (SD) | 14 (6) | 15 (7) | 17 (6)b |
| Without population | 14 (6) | 15 (7) | 17 (6)b |
| Hemodynamic characteristics | |||
| ICI (median) (IQR) | 0.4 (0.2–1.0) | 0.5 (0.3–1.2) | 0.6 (0.3–1.2) |
| SR (median) (IQR) (1/s) | 207.3 (124.0–317.5) | 190.1 (67.8–273.7) | 126.3 (65.1–177.0)a |
| VE (median) (IQR) (cm/s) | 9.4 (5.9–13.6) | 8.0 (4.6–11.4) | 6.6 (3.8–10.2)b |
| VO (median) (IQR) (1/s) | 270.5 (165.5–416.2) | 256.9 (93.9–384.5) | 177.5 (88.3–255.0)a |
| Max WSS (median) (IQR) (dyne/cm2) | 175.2 (126.8–239.2) | 149.5 (107.6–194.5)c | 146.8 (94.7–186.1)b |
| Mean WSS (median) (IQR) (dyne/cm2) | 17.5 (11.2–29.9) | 16.5 (6.5–24.2) | 11.5 (5.4–18.8)a |
| LSA (median) (IQR) (%) | 54 (29–74) | 53 (31–77) | 68 (50–89)c |
| SCI (median) (IQR) | 3.2 (1.9–4.6) | 2.7 (1.0–4.2) | 3.2 (0.2–5.7) |
| Max OSI (median) (IQR) | 0.3 (0.1–0.4) | 0.2 (0.2–0.4) | 0.3 (0.2–0.4) |
| Mean OSI (median) (IQR) | 0.01 (0.01–0.01) | 0.01 (0.0–0.01) | 0.01 (0.01–0.02) |
| CLL (median) (IQR) | 0.7 (0.2–1.4) | 0.6 (0.4–1.5) | 1.1 (0.5–2.0)c |
| PODE (median) (IQR) | 0.1 (0.1–0.2) | 0.1 (0.1–0.2) | 0.2 (0.1–0.3) |
Note:–ACA indicates anterior cerebral artery; AcomA, anterior communicating artery; PcomA, posterior communicating artery; Q, flow rate; ICI, inflow concentration index; SR, mean aneurysm shear rate; SCI, shear concentration index; max, maximum. P-value compared to stable aneurysms.
↵a P < .001.
↵b P < .02.
↵c P < .05.