Table 1:

Subgroups of NCL, their genes, protein names, and MIM numbers

Locus NameGene SymbolProtein NameMIM Number
CLN1PPT1Palmitoyl protein thioesterase 1600722
CLN2TPP1Tripeptidyl peptidase 1607998
CLN3CLN3CLN3607042
CLN4DNAJC5DnaJ homolog611203
CLN5CLN5CLN5608102
CLN6CLN6CLN6601780
CLN7MFSD8Major facilitator superfamily611124
CLN8CLN8CLN8607837
CLN9N/AUnknown609055
CLN10CTSDCathepsin D116840
CLN11GRNGranulins138945
CLN12ATP13A2Probable cation transporting610513
CLN13CTSFCathepsin F603539
CLN14KCTD7BTB/POZ domain-containing611725
  • Note:—MIM indicates Mendelian Inheritance in Man; N/A, not applicable.