Table 1:

Consensus recommendations for the dosage of GPIIb/IIIa receptor inhibitorsa

AgentTirofibanEptifibatideAbciximab
Loading dose (IV or IA bolus)12 mcg/kg for 30 minb180 mcg/kg for 1–2 min0.25 mg/kg
Maintenance dose (if necessary, IV infusion for 12–24 h)0.1 mcg/kg/min2 mcg/min125 mcg/kg/min
Trade nameAggrastatIntegrilinReoPro
Duration of antiplatelet effect4–8 h4 h48 h

  • Note:—IA indicates intra-arterial.

  • ↵a Dosages are suggestions based on the panel consensus and may vary according to local availability of dosages.

  • ↵b 0.4 mcg/kg/min.