Table 3:

Association between risk factors of cardiovascular disease and heavy burden and vulnerability of intracranial plaques

Univariate RegressionMultivariate Regressiona
OR95% CIP ValueOR95% CIP Value
Plaque length
 Male1.7891.095–2.924.0201.8641.132–3.068.014
 Poor glycemic control1.8881.132–3.150.0151.9661.170–3.303.011
Plaque thickness
 Low HDL1.8331.168–2.876.0081.7391.102–2.745.017
 Poor glycemic control2.0911.247–3.507.0051.9811.174–3.340.010
Severe lumen stenosis
 Poor glycemic control1.9621.169–3.294.0111.9621.169–3.294.011
Strong enhancement
 Low HDL2.2131.329–3.685.0022.0461.208–3.465.008
 Poor glycemic control5.7582.534–13.085<.0015.4482.385–12.444<.001
  • Note:—LDL indicates low-density lipoprotein cholesterol; HDL, high-density lipoprotein cholesterol.

  • a Multivariate logistic regression adjusted for age, smoking, hypertension, history of coronary artery disease, and family history of cardiovascular disease.