Group | Diagnosis | Sex | Age (yr) | Clopidogrel Resistance | PRU | % Inhibition | Thromboembolic Event | 30-Day Follow-Up |
---|---|---|---|---|---|---|---|---|
A | Bilateral carotid artery dissection | Female | 53 | Yes | 298 | 3% | Post-op in-stent thrombosis with TIA, required 1 ECA-ICA bypass | Normal |
A | Right internal carotid artery occlusion, secondary to right carotid artery dissection | Male | 42 | Yes | 291 | 0% | Perioperative R frontal stroke | Normal (recovered) |
A | Basilar apex aneurysm | Female | 48 | Yes | 289 | 0% | R cerebellar stroke POD 1 | Dizziness (resolved) |
A | Right MCA stenosis | Female | 77 | Yes | 235 | 0% | Intra-op in-stent thrombus formation treated with IA abciximab; right basal ganglia stroke | Nonfocal; psychomotor retardation |
A | Left hemisphere subcortical subacute infarct, left MCA severe stenosis | Male | 68 | Yes | 360 | 0% | Periprocedural in-stent thrombosis, required ECA-ICA bypass | Dysarthria and R hemiparesis |
B | Giant left MCA aneurysm | Male | 75 | Yes | 243 | 0% | Stroke after being decreased from double clopidogrel dose | Right-handed weakness (resolved) |
B | MCA stenosis | Male | 79 | No | 30 | 80% | L MCA small vessel stroke in the MCA stent distribution | Mild word-finding difficulty (resolved) |
Note:—ECA indicates external carotid artery; R, right; POD, post-operative day; intra-op, introperative; L, left; PcomA, posterior communicating artery; IA, intra-arterial; PCA, posterior cerebral artery; Post-op, postoperative; periop, perioperative.