Clinical characteristics for very preterm infants with neurodevelopmental assessments at 3 years' CA

Baseline CharacteristicsaFinal Cohort (n = 69)Excluded (n = 32)P
Maternal age (mean) (SD) (yr)30.2 (6.0)30.1 (6.1).96
Antenatal corticosteroid therapy (any)64 (92.8%)23 (71.9%).01
Multiple gestation24 (34.8%)9 (28.1%).51
Male sex39 (56.5%)15 (46.9%).37
Gestational age (mean) (SD) (wk)28.4 (2.5)28.1 (2.5).68
Birth weight (mean) (SD) (g)1121.4 (394.1)1131.6 (398.1).91
5-Minute Apgar score <512 (17.4%)9 (29.0%)b.20
Late-onset sepsis (culture-positive)9 (13.0%)4 (12.5%)1.00
Severe bronchopulmonary dysplasia22 (31.9%)10 (31.3%)1.00
Severe retinopathy of prematurity8 (11.6%)1 (3.1%).27
Surgery requiring general anesthesia9 (13.0%)7 (21.9%).26
MR imaging global brain abnormality score (median) (range)2 (0–9)3 (0–23).51
Postmenstrual age at MR imaging (mean) (SD) (wk)40.4 (0.6)40.6 (0.8).35
Cerebral palsy diagnosis, cases/total (%)7/65 (10.8%)2/20 (10.0%)1.00
  • a All data are No. (%) unless otherwise stated.

  • b Data missing for 1 subject born at home.