Uncorrected hippocampal subfield, total hippocampal, and intracranial volumes measured by FreeSurfer and volBrain protocolsa

Total (n = 172)Male (n = 83)Female (n = 89)Cohen’s D
MeanSDMeanSDMeanSD
FreeSurfer v6.0
 CA11251193132116911841590.83
 CA2-CA34727149751449540.91
 CA4-DG1113171117314110571350.84
 Subiculum807102841101775870.7
 Parasubiculum1212112616117210.48
 Presubiculum5537258175527590.8
 Molecular layer1205168124113611721500.48
 HATA1363114219130230.57
 Fimbria1786718862168480.36
 Tail99916010491559521180.7
 Fissureb2697127649262700.23
 THV6839957716384665377580.78
 eICV1,563,261146,9831,677,235158,9671,456,885231,3101.11
volBrain, HIPS segmentation protocol
 CA11486286157426714052340.67
 CA2-CA32643727643253320.61
 CA4-DG1420221146220713822600.34
 SR-SL-SM9381589881738921450.6
 Subiculum5668759386541930.58
 THV4689771490877644846650.59
 eICV1,374,768133,4671,462,729139,9051,292,671126,1291.28
  • Note:—HATA indicates hippocampus-amygdala transition area; eICV, estimated intracranial volume; HIPS, hippocampal subfield segmentation protocol.

  • a Uuits are cubic millimeters.

  • b Not significantly different. Men had significantly larger values than females in all volumes, except hippocampus fissure (P < .05, Student t test). The average values of total and subfield volumes reported here are the sum of right and left hemispheres combined.