Elsevier

Experimental Eye Research

Volume 73, Issue 5, November 2001, Pages 581-592
Experimental Eye Research

Review
Shifting the Paradigm of the Blood–Aqueous Barrier

https://doi.org/10.1006/exer.2001.1056Get rights and content

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References (54)

  • R. Uusitalo et al.

    An electron microscopical study of the blood–aqueous barrier in the ciliary body and iris of the rabbit

    Exp. Eye Res.

    (1973)
  • W.S. Wilson et al.

    Iris delay, a neglected factor in aqueous humor dynamics. A study in the cynomolgus monkey (Macaca fascicularis)

    Exp. Eye Res.

    (1983)
  • E.H. Barany et al.

    Hyaluronic acid and hyaluronidase in the aqueous humor and the angle of the anterior chamber

    Acta Physiol. Scand.

    (1955)
  • M.F. Barsotti et al.

    The source of protein in the aqueous humor of the normal monkey eye

    Invest. Ophthalmol. Vis. Sci.

    (1992)
  • T.L. Beardsley et al.

    Effect of timolol on aqueous humor protein concentration in humans

    Am. J. Ophthalmol.

    (1983)
  • R. Bert et al.

    Confirmation of anterior large-molecule diffusion pathway in the normal human eye

    Invest. Ophthalmol. Vis. Sci.

    (1999)
  • A. Bill

    Capillary permeability to and extravascular dynamics of myoglobin, albumin and gammaglobulin in the uvea

    Acta Physiol. Scand.

    (1968)
  • A. Bill

    The blood–aqueous barrier

    Trans. Ophthalmol. U.K.

    (1986)
  • J. Cuhna-Vaz

    The blood-ocular barriers

    Surv. Ophthalmol.

    (1979)
  • H. Davson

    Physiology of the Eye

    (1990)
  • J.P. Dernochamps et al.

    Molecular sieve effect of the blood–aqueous barrier

    Exp. Eye Res.

    (1975)
  • J.P. Dernochamps et al.

    Molecular sieve properties of the blood–aqueous barrier in uveitis

    Exp. Eye Res.

    (1977)
  • E.W. Doss et al.

    Investigation of the ‘fines’ hypothesis of primary open-angle glaucoma; the possible role of alpha-crystallin

    Ophthalmic Res.

    (1998)
  • T. Freddo

    Intercellular junctions of the iris epithelia in Macaca mulatta

    Invest. Ophthalmol. Vis. Sci.

    (1984)
  • T.F. Freddo et al.

    The source of proteins in the aqueous humor of the normal rabbit

    Invest. Ophthalmol. Vis. Sci.

    (1990)
  • T.F. Freddo et al.

    Pathway of albumin into the anterior chamber

    Graefe's Arch. Clin. Exp. Ophthalmol.

    (1995)
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    Address correspondence to: Thomas F. Freddo, Eye Pathology Lab, L-905, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, U.S.A.

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