Regular ArticleMotor Neurone Disease-inclusion Dementia
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2009, Neurobiology of AgingCitation Excerpt :In terms of neuropathology, most SD cases (72%) conform to a single subtype of FTD, with intra-neuronal deposits containing the protein ubiquitin (Davies et al., 2005). Such deposits are also described in motor neuron disease (MND) and are sometimes termed MND inclusions (Jackson et al., 1996). Patient with clinical features of FTD (typically behavioural disturbance and reduced fluency of speech) with signs of MND are increasingly recognized, and may be labelled ‘FTD–MND’ (Lomen-Hoerth et al., 2002, 2003; Neary et al., 1990; Rakowicz and Hodges, 1998).
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