Regular ArticleFormation of Paramagnetic Chromium in Liver of Mice Treated with Dichromate (VI)
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An overview on the potential mechanisms of action of N-acetyl-l-cysteine in hexavalent chromium-induced toxicity
2020, Toxicology: Oxidative Stress and Dietary AntioxidantsEPR detection of paramagnetic chromium in liver of fish (Anguilla anguilla) treated with dichromate(VI) and associated oxidative stress responses - Contribution to elucidation of toxicity mechanisms
2013, Comparative Biochemistry and Physiology - C Toxicology and PharmacologyCitation Excerpt :The spectra obtained in the present study were similar to those described in the literature for different tissues and different vertebrate species after treatment with Cr(VI), namely chick embryo red blood cells (Liebross and Wetterhahn, 1992), mammalian cell lines (Sugiyama, 1994; Levina et al., 2007) and mice liver (Ueno et al., 1995). In particular, Ueno et al. (1995) noted that the signal marked as R was detected in all the samples regardless the time elapsed after Cr administration, as well as prior to the treatment, and concluded that it was due to constitutive free radicals in the liver. These authors also used the peak-to-peak height of the Cr(V) signal, normalized to the sample mass, in order to follow the amount of this chemical species, in spite of that the shape of the signal appears slightly dependent of the time after the metal administration.
Detection and structural characterization of Oxo-Chromium(V)-sugar complexes by electron paramagnetic resonance
2011, Advances in Carbohydrate Chemistry and BiochemistryCitation Excerpt :Further in vivo experiments using sialic acid-bound biological matrices are currently being conducted to assess the nature of the Cr(VI)-induced damage to cell-bound sialic acid residues. Since sialic acid residues are involved in the control of fundamental cell processes,106 any oxidative or alternative damage to these residues might have deleterious consequences on cell behavior. Normal human bronchial epithelial cells generate Cr(V) from both Na2CrO4 (soluble) and ZnCrO4 (insoluble).
Mutagenicity of sediment and biomarkers of oxidative stress in fish from aquatic environments under the influence of tanneries
2004, Mutation Research - Genetic Toxicology and Environmental MutagenesisOxidative stress damage in the liver of fish and rats receiving an intraperitoneal injection of hexavalent chromium as evaluated by chemiluminescence
2004, Environmental Toxicology and Pharmacology