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fMRI in Epilepsy

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Book cover fMRI Techniques and Protocols

Part of the book series: Neuromethods ((NM,volume 41))

Summary

This chapter provides an overview of the application of functional MRI applied to the field of Epilepsy and is divided into two sections, covering cognitive mapping and imaging of paroxysmal activity, respectively. In addition to a review of the most scientifically and clinically relevant findings, technical and methodological background information is provided to help the reader better understand the data acquisition process. We show how both approaches may play a role in the pre-surgical evaluation of patients with drug-resistant focal epilepsy and provide opportunities for new insights into the neuropathological processes that underlie both focal and generalised epilepsy.

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Acknowledgments

Thanks to Philip Allen for his comments on parts of the manuscript and to Dr. Anna Vaudano and Dr. Serge Vulliemoz for supplying some of the illustrations. Some of the work reported in this chapter was funded through a grant from the Medical Research Council (MRC grant number G0301067) and by the Wellcome Trust. We are grateful to the Big Lottery Fund, Wolfson Trust, and National Society for Epilepsy for supporting the NSE MRI scanner. This work was carried out under the auspices of the UCL/UCLH Biomedical Comprehensive Research Centre.

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Authors and Affiliations

  1. Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, Queen Square, WC1N 3BG, London, UK

    Rachel Thornton, Robert Powell & Louis Lemieux

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  1. Rachel Thornton
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  2. Robert Powell
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  3. Louis Lemieux
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Correspondence to Louis Lemieux .

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  1. Ospedale San Raffaele, Università Milano-Bicocca, Via Olgettina 60, Milano, 20132, Italy

    Massimo Filippi

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© 2009 Humana Press, a part of Springer Science+Business Media, LLC

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Thornton, R., Powell, R., Lemieux, L. (2009). fMRI in Epilepsy. In: Filippi, M. (eds) fMRI Techniques and Protocols. Neuromethods, vol 41. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60327-919-2_23

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  • DOI: https://doi.org/10.1007/978-1-60327-919-2_23

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-60327-918-5

  • Online ISBN: 978-1-60327-919-2

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