Skip to main content
Log in

MRI in acute transverse myelopathy

  • Diagnostic Neuroradiology
  • Published:
Neuroradiology Aims and scope Submit manuscript

Summary

The MRI examinations of seven patients with acute transverse myelopathy (ATM) were analysed. The patients were examined 2–5 times during the course of their disease with short and long TR/TE spin-echo sequences in the sagittal projection. A previous history of autoimmune disorder and/or signs of infection at the onset of ATM were present in all cases. Cerebrospinal fluid analysis showed local synthesis of immunoglobulin in the nervous system in three cases and signs of infectious myelitis in one. During the acute phase four patients had local enlargement of the cord and all had increased signal on long TR/TE sequences. The outcome was grave in the majority of patients and there seemed to be a correlation between the degree of cord enlargement, persistence of increased signal intensity and limited recovery. Atrophy and remaining high signal intensity were noted on late MRI in patients with poor outcome. In one patient with probable anterior spinal artery occlusion, cavitation of the cord was seen.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Altrocchi PH (1963) Acute transverse myelopathy. Arch Neurol 9:111–119

    Google Scholar 

  2. Lipton HL, Teasdall RD (1973) Acute transverse myelopathy in adults A follow-up study. Arch Neurol 28:252–257

    Google Scholar 

  3. Ropper AH, Poskanzer DC (1978) The prognosis of acute and subacute transverse myelopathy based on early signs and symptoms. Ann Neurol 4:51–59

    Google Scholar 

  4. Paine RS, Byers RK (1953) Transverse myelopathy in childhood. Am J Dis Child 85:151–163

    Google Scholar 

  5. Dunne, K, Hopkins IJ, Shield LK (1986) Acute transverse myelopathy in childhood. Dev Med Child Neurol 28:198–204

    Google Scholar 

  6. Sands ML, Ryczah MJ, Brown RB (1988) Recurent aseptic meningitis followed by transverse myelitis as a presentation of systemic lupus erythematosus. J Rheumatol 15:862–863

    Google Scholar 

  7. Pedersen C, Bonen H, Boesen F (1987) Transverse myelitis in mixed connective tissue disease. Case report. Clin Rheumatol 6: 290–292

    Google Scholar 

  8. Rutan G, Martinez AJ, Fieshko JT, Thiel DH van (1986) Primary biliary cirrhosis, Sjogren's syndrome, and transverse myelitis. Gastroenterology 90, 206–210

    Google Scholar 

  9. Kenik JG, Krohn K, Kelly RB, Bierman M, Hammeke D, Hurley A (1987) Transverse myelitis and optic neuritis in systemic lupus erythematosus: a case report with magnetic resonance imaging findings. Arthritis Rheum 30:947–950

    Google Scholar 

  10. Warren RW, Kredich DW (1984) Transverse myelitis and acute central nervous system manifestations of systemic lupus erythematosus. Arthritis Rheum 27:1058–1060

    Google Scholar 

  11. Andrianakos AA, Duffy J, Suzuki M, Sharp JT (1975) Transverse myelopathy in systemic lupus erythematosus. Ann Intern Med 83:616–623

    Google Scholar 

  12. Berman M, Feldman S, Alter M, Zilber N, Kahana E (1981) Acute transverse myelitis: incidence and etiologic considerations. Neurology 31:966–971

    Google Scholar 

  13. Merine D, Wang H, Kumar AJ, Zinreich SJ, Rosenbaum AE (1987) CT myelography and MR imaging of acute transverse myelitis. J Comput Assist Tomogr 11:606–608

    Google Scholar 

  14. Bitzan M (1987) Rubella myelitis and encephalitis in childhood. A report of two cases with magnetic resonance imaging. Neuropediatrics 18:84–87

    Google Scholar 

  15. Aichner F, Poewe W, Rogalsky W, Wallnöfer K, Willeit J, Gerstenbrand F (1985) Magnetic resonance imaging in the diagnosis of spinal cord diseases. J Neurol Neurosurg Psychiatry 48:1220–1229

    Google Scholar 

  16. Barakos JA, Mark AS, Dillon WP, Norman D (1990) MR imaging of acute transverse myelitis and AIDS myelopathy. J Comput Assist Tomogr 14:45–50

    Google Scholar 

  17. Christensen PB, Wermuth L, Hinge HH, Bömers K (1990) Clinical course and long-term prognosis of acute transverse myelopathy. Acta Neurol Scand 81:431–435

    Google Scholar 

  18. Heck AW, Phillips LH (1989) Sarcoidosis and the nervous system. Neurological manifestations of systemic disease. Neurol Clin 7:641–654

    Google Scholar 

  19. Bogousslavsky J, Hungerbühler JP, Regli F, Graf HJ (1982) Subacute myelopathy as presenting manifestation of sarcoidosis. Acta Neurochir (Wien) 65:193–197

    Google Scholar 

  20. Brick JE, Brick JF (1989) Neurological manifestation of rheumatologic disease. Neurologic manifestation of systemic disease. Neurol Clin 7:629–639

    Google Scholar 

  21. Westenfelder GO, Akey DT, Corwin SJ, Vick NA (1981) Acute transverse myelitis due to Mycoplasma pneumoniae infection. Arch Neurol 38:317–318

    Google Scholar 

  22. Clyde WA (1980) Neurological syndromes and mycoplasmal infections. Arch Neurol 37:65–66

    Google Scholar 

  23. Larsson EM, Holtas S, Nilsson O (1989) Gd-DTPA-enhanced MR of suspected spinal multiple sclerosis. AJNR 10:1071–1076

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Holtås, S., Basibüyük, N. & Fredriksson, K. MRI in acute transverse myelopathy. Neuroradiology 35, 221–226 (1993). https://doi.org/10.1007/BF00588501

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00588501

Key words

Navigation