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Experimental saccular aneurysms

I. Review of surgically-constructed models and their laboratory applications

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Abstract

Experimental models of intracranial saccular ancurysms are a useful contribution to our basic understanding of these lesions. Currently, the commonest in use are those constructed surgically in laboratory animals. We review the numerous surgical techniques available since the 1950s, and the research applications and uses of experimental aneurysms. Further development and use of such models is greatly encouraged in future pathophysiological, hemodynamic, and therapeutic investigations of intracranial saccular aneurysms.

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Authors and Affiliations

  1. Endovascular Therapy Service and Leo G.Rigler Radiological Research Center, Department of Radiological Sciences, UCLA Medical Center, 10833 Le Conte Avenue, 90024-1721, Los Angeles, CA, USA

    T. F. Massoud, G. Guglielmi, C. Ji, F. Viñuela & G. R. Duckwiler

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  1. T. F. Massoud
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  2. G. Guglielmi
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  3. C. Ji
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  4. F. Viñuela
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  5. G. R. Duckwiler
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Massoud, T.F., Guglielmi, G., Ji, C. et al. Experimental saccular aneurysms. Neuroradiology 36, 537–546 (1994). https://doi.org/10.1007/BF00593517

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