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Cerebrovascular occlusive complications in osteopetrosis major

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Summary

We report the case of a 16-year-old patient with osteopetrosis major, complaining of transient sensory and motor disturbances in the left upper limb and diziness on changing the position of his head. Selective angiography of the cerebral vessels showed severe narrowing of the internal carotid artery within the petrous carotid canal and in its supraclinoid portion. The cervical vertebral arteries showed multiple stenosis within the vertebral canal. These findings are explained by narrowing of the basal foramina by the osteopetrotic bone.

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References

  1. Albers-Schonberg H (1904) Rottengilder einer seltenen Knochenerkrankung. Munch Med Wochenschr 51: 365–368

    Google Scholar 

  2. Gamsu H, Lorrer J, Rendle-Short J (1961) Hemolytic anemia in osteopetrosis. Arch Dis Child 36: 494–499

    Article  PubMed  CAS  Google Scholar 

  3. Klintworth GK (1963) The neurological manifestigations of osteopetrosis (Albers-Schonberg's disease). Neurology 13: 512–519

    PubMed  CAS  Google Scholar 

  4. Lehman RAW, Reeves JD, Wilson WB, Wesenberg RL (1977) Neurological complications of infantile osteopetrosis. Ann Neurol 2: 378–384

    Article  PubMed  CAS  Google Scholar 

  5. Turano AF, Fagan KA, Corbo PA (1954) Variations in clinical manifestations of osteopetrosis. J Pediatr 44: 688–694

    Article  PubMed  CAS  Google Scholar 

  6. Makin GJV, Coates RK, Pelz D, Drake CG, Barnett HJM (1986) Major cerebral arterial and venous disease in osteopetrosis. Stroke 17: 106–110

    PubMed  CAS  Google Scholar 

  7. Krane SM, Schiller AL (1982) Hyperostosis, neoplasms, and other disorders of bone and cartilage. In: Petersdorf RG, Adams RD, Braunwald E, Isselbacher KJ, Martin JB, Wilson JD (eds) Harrison's principles of internal medicine. Me Graw Hill, New York

    Google Scholar 

  8. Ellis PO, Jackson WE (1962) Osteopetrosis: a clinical evaluation of optic nerve involvement. Am J Ophthalmol 53: 943–953

    PubMed  CAS  Google Scholar 

  9. Keith CG (1968) Retinal atrophy in osteopetrosis. Arch Ophthalmol 79: 234–241

    PubMed  CAS  Google Scholar 

  10. Hoyt CS, Billson FA (1979) Visual loss in osteopetrosis. Am J Dis Child 133: 955–958

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Radiology Division of Paediatric Neurology, University Hospitals K. U. Leuven, Herestraat 49, B-3000, Leuven, Belgium

    G. Wilms, P. Demaerel, M. Smet & A. L. Baert

  2. Department of Pediatrics, Division of Paediatric Neurology, University Hospitals K. U. Leuven, Belgium

    P. Casaer & P. Alliet

Authors
  1. G. Wilms
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  2. P. Casaer
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  3. P. Alliet
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  4. P. Demaerel
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  5. M. Smet
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  6. A. L. Baert
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Wilms, G., Casaer, P., Alliet, P. et al. Cerebrovascular occlusive complications in osteopetrosis major. Neuroradiology 32, 511–513 (1990). https://doi.org/10.1007/BF02426467

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  • DOI: https://doi.org/10.1007/BF02426467

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