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Management of Unruptured Saccular Aneurysms of the M1 Segment with Flow Diversion

A Single Centre Experience

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Abstract

Purpose

The optimal strategy for the treatment of M1 segment aneurysms has not yet been determined as both standard microneurosurgical and endovascular techniques can pose challenges. We sought to determine the efficacy of flow diverting stents to treat small, unruptured aneurysms of the M1 segment.

Methods

We retrospectively reviewed our database of prospectively collected information for all patients treated with flow diversion for an unruptured saccular aneurysm of the middle cerebral artery (MCA) between February 2009 and February 2016. The relationship to early cortical branches, aneurysm fundus size, number and type of flow diverting stent (FDS), complications and follow-up data were recorded.

Results

In total 15 patients were identified that matched our inclusion criteria (11 female and 4 male). The average age of the patients was 58.3 years (range 14–76 years). All patients had a single aneurysm affecting the M1 segment of the MCA, 10 (66.6%) of which were related to early cortical branches and 10 aneurysms were located on the left (66.6%). The average aneurysm fundus size was 3 mm (range 2–9 mm) and 13 patients had follow-up angiographic studies. In total, 8 aneurysms were completely excluded, and 6 remained incompletely occluded (3 modified Raymond-Roy classification [mRRC] II and 3 mRRC IIIa). One patient suffered a stroke and another patient had an iatrogenic vessel dissection that was not flow limiting.

Conclusion

Flow diversion can be used to treat small, unruptured aneurysms of the M1 segment of the MCA and even though side vessel occlusion can occur clinically relevant infarction occurs infrequently.

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Authors and Affiliations

  1. Neuroradiological Clinic, Neurocenter, Klinikum Stuttgart, Kriegsbergstrasse 60, 70174, Stuttgart, Germany

    Pervinder Bhogal, Rosa Martinez, Hans Henkes & Marta Aguilar

  2. Neurological Clinic, Neurocenter, Klinikum Stuttgart, Stuttgart, Germany

    Hansjörg Bäzner

  3. Neurosurgical Clinic, Neurocenter, Klinikum Stuttgart, Stuttgart, Germany

    Oliver Gansladt

  4. Medical Faculty, University Duisburg-Essen, Essen, Germany

    Hans Henkes

Authors
  1. Pervinder Bhogal
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  2. Rosa Martinez
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  3. Oliver Gansladt
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  4. Hansjörg Bäzner
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  5. Hans Henkes
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  6. Marta Aguilar
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Corresponding author

Correspondence to Pervinder Bhogal.

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Conflict of interest

M. Aguilar, P. Bhogal and R. Martinez serve as proctors and consultants for phenox GmbH, with moderate financial compensation. H. Henkes is a co-founder and shareholder of phenox GmbH. O. Gansladt and H. Bäzner declare that they have no competing interests.

All studies on humans described in the present article were carried out in accordance with national law and the Helsinki Declaration of 1964 (in its present revised form). Ethics committee approval was not necessary. Informed consent was obtained from all patients included in the studies.

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Bhogal, P., Martinez, R., Gansladt, O. et al. Management of Unruptured Saccular Aneurysms of the M1 Segment with Flow Diversion. Clin Neuroradiol 28, 209–216 (2018). https://doi.org/10.1007/s00062-016-0553-9

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  • DOI: https://doi.org/10.1007/s00062-016-0553-9

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