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Further Development of Combined Techniques Using Stent Retrievers, Aspiration Catheters and BGC

The PROTECTPLUS Technique

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Abstract

Purpose

First pass complete (mTICI 3) reperfusion must be regarded as the ultimate goal in mechanical thrombectomy (MT) in patients suffering from an emergent large vessel occlusion (ELVO). With this in mind a technical modification of the previously published PROTECT (PRoximal balloon Occlusion TogEther with direCt Thrombus aspiration during stent retriever thrombectomy) approach, the PROTECTPLUS technique was evaluated. Under proximal flow arrest using a balloon guide catheter (BGC), a stent retriever was only partially inserted into a large-bore aspiration catheter. This construction was subsequently retracted as a unit into the BGC with aspiration both at the aspiration catheter and at the BGC.

Methods

A case-control study was performed comparing the PROTECT technique with the PROTECTPLUS technique with respect to the technical and procedural parameters. Patients n = 165 (101 PROTECT, 64 PROTECTPLUS) with ELVO of either the terminus of the internal carotid artery or the proximal middle cerebral artery were included.

Results

Using the PROTECTPLUS resulted in a higher rate of first pass complete reperfusions (59.4% vs. 27.7%, p < 0.001) as compared with PROTECT. The PROTECTPLUS also led to shorter procedure times (21 min vs. 37 min, p = 0.001) and higher rates of overall complete reperfusion (73.5% vs. 49.5%, p = 0.014) compared to PROTECT.

Conclusion

The PROTECTPLUS technique is a promising technical modification to further optimize endovascular stroke treatment.

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Authors and Affiliations

  1. Department of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, Technical University Munich, Ismaninger Str. 22, 81675, Munich, Germany

    Christian Maegerlein, Maria Teresa Berndt, Sebastian Mönch, Kornelia Kreiser, Tobias Boeckh-Behrens, Manuel Lehm, Claus Zimmer & Benjamin Friedrich

  2. Department of Neurology, Klinikum rechts der Isar, Technical University Munich, Munich, Germany

    Silke Wunderlich

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  1. Christian Maegerlein
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  2. Maria Teresa Berndt
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  3. Sebastian Mönch
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  8. Claus Zimmer
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Correspondence to Christian Maegerlein.

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Conflict of interest

C. Maegerlein reports minor travel grants and personal fees from Stryker Neurovascular and Penumbra. M.T. Berndt, S. Mönch, K. Kreiser, T. Boeckh-Behrens, M. Lehm, S. Wunderlich, C. Zimmer and B. Friedrich declare that they have no competing interests.

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Neither approval of the institutional review board nor patient informed consent are required by the ethics committee of the institution for retrospective analyses of patient records and imaging data.

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Maegerlein, C., Berndt, M.T., Mönch, S. et al. Further Development of Combined Techniques Using Stent Retrievers, Aspiration Catheters and BGC. Clin Neuroradiol 30, 59–65 (2020). https://doi.org/10.1007/s00062-018-0742-9

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  • DOI: https://doi.org/10.1007/s00062-018-0742-9

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