Abstract
Background and Purpose
In vasculopathies of the central nervous system, reliable and timely diagnosis is important against the background of significant morbidity and sequelae in cases of incorrect diagnosis or delayed treatment. Magnetic resonance imaging (MRI) plays a major role in the detection and monitoring of intracranial and extracranial vascular pathologies of different etiologies, in particular for evaluation of the vessel wall in addition to luminal information, thus allowing differentiation between various vasculopathies. Compressed-sensing black-blood MRI combines high image quality with relatively short acquisition time and offers promising potential in the context of neurovascular vessel wall imaging in clinical routine. This case review gives an overview of its application in the diagnosis of various intracranial and extracranial entities.
Methods
An optimized high-resolution compressed-sensing black-blood 3D T1-weighted fast (turbo) spin echo technique (T1 CS-SPACE prototype) precontrast and postcontrast application at 3T was used for the evaluation of various vascular conditions in neuroradiology.
Results
In this article seven cases of intracranial and extracranial arterial and venous vasculopathies with representative imaging findings in high-resolution compressed-sensing black-blood MRI are presented.
Conclusion
High-resolution 3D T1 CS-SPACE black-blood MRI is capable of imaging various vascular entities in high detail with whole head coverage and low susceptibility for motion artifacts and within acceptable scan times. It represents a highly versatile, non-invasive technique for the visualization and differentiation of a wide variety of neurovascular arterial and venous disorders.
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Acknowledgements
Grant support by the Deutsche Forschungsgemeinschaft (DFG) under grant numbers DFG HE 1875/26‑2, and BL1132/1‑2 is greatly acknowledged.
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K. Guggenberger, A.J. Krafft, U. Ludwig, P. Vogel, S. Elsheik, E. Raithel, C. Forman, P. Dovi-Akué, H. Urbach, T. Bley and S. Meckel declare that they have no competing interests.
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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1975 Helsinki declaration and its later amendments or comparable ethical standards. All patients gave their informed consent for the use of their data prior to inclusion in the study.
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Guggenberger, K., Krafft, A.J., Ludwig, U. et al. High-resolution Compressed-sensing T1 Black-blood MRI. Clin Neuroradiol 31, 207–216 (2021). https://doi.org/10.1007/s00062-019-00867-0
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DOI: https://doi.org/10.1007/s00062-019-00867-0