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Endovaskuläre Eingriffe in der interventionellen Neuroradiologie

Neue Aspekte

Endovascular interventions in neuroradiology

New aspects

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Zusammenfassung

Die interventionelle Neuroradiologie (INR) hat sich in den letzten 10 Jahren insbesondere in der Aneurysmabehandlung und in der akuten ischämischen Schlaganfallbehandlung etabliert, sodass die Zahl der Eingriffe, aber auch die Standorte mit spezieller neuroradiologischer Expertise zugenommen haben. Viele Eingriffe sind mittlerweile als Routine einzuordnen, sodass auch Routine und Prozessoptimierung für die interdisziplinäre Zusammenarbeit zwischen Neuroradiologie und Anästhesie Voraussetzung für Patientenschutz und einen reibungslosen Ablauf sind. Routine bedeutet hierbei, dass das Wissen um die Erkrankung und die Art der Behandlung sowie die gegenseitigen Anforderungen und Erwartungen von Interventionalist und Anästhesist bekannt sind. Zu differenzieren gilt der Notfalleingriff, bei dem die zeitlichen Abläufe kurz gehalten werden müssen, von dem elektiven Eingriff, der geplant unter optimierten Bedingungen ablaufen kann. Im vorliegenden Beitrag werden allgemeine Voraussetzungen hierfür benannt. Diskutiert werden die zwei häufigsten Interventionen: Behandlungen von Aneurysmen und Rekanalisationsbehandlungen beim akuten Schlaganfall.

Abstract

In the last 10 years interventional neuroradiology has become established especially in the endovascular treatment of aneurysms as the preferred treatment according to level 1 evidence and more recently in the treatment of acute ischemic stroke. These interventions are performed as routine procedures in an increasing number of centers. This, however, necessitates that anesthesiologists and neuroradiologists become increasingly more familiar with the complementary expectations and potential pitfalls in working together to maximise efficiency and patient safety. As a further challenge there are different aspects to be considered in elective procedures and emergency procedures where time is brain. This article highlights these aspects for the two most common procedures: aneurysm treatment and multimodal recanalization treatment for acute ischemic stroke.

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Abbreviations

ACI:

A. carotis interna

ACT:

„activated clotting time“

ASS:

Acetylsalicylsäure

AVF:

arteriovenöse Fistel

AVM:

arteriovenöse Malformation

BRAT:

Barrow Ruptered Aneurysm Trial

CARAT:

Cerebral Aneurysm Rerupture After Treatment

CT:

Computertomogramm

EKG:

Elektrokardiogramm

GREAT:

German Randomized Endovascular Aneurysm Trial

GP IIa/IIIb:

Glykoprotein IIb/IIIa

HELPS:

Hydrogel-coated Coils versus Bare Platinum Coils for the Endovascular Treatment of Intracranial Aneurysms

ICP:

„intracranial pressure“ (intrakranialer Druck)

IMS:

Interventional Management of Stroke

INR:

interventionelle Neuroradiologie

ISAT:

International Subarachnoid Aneurysm Trial

ISUIA:

International Study of Unruptured Intracranial Aneurysms

ITN:

Intubationsnarkose

IVT:

intravenöse Thrombolyse

LIF:

lokale intraarterielle Fibrinolyse

LMW:

„low molecular weight“

MAP:

„mean arterial pressure“ (mittlerer arterieller Druck)

MAPS:

Matrix and Platinum Science (Trial)

MR RESCUE:

Mechanical Retrieval and Recanalization of Stroke Clots Using Embolectomy

mRS:

modified Rankin Score

NIHSS:

National Institutes of Health Stroke Scale

p.-a.:

posterior-anterior (Strahlengang)

PROACT:

Prolyse in Acute Cerebral Thromboembolism

PTA:

perkutane transluminale Angioplastie

PTT:

„partial thromboplastin time“ (partielle Thromboplastinzeit)

rt-PA:

„recombinant tissue-type plasminogen activator“

SAB:

Subarachnoidalblutung

SAMMPRIS:

Stenting and Aggressive Medical Management for Preventing Recurrent stroke in Intracranial Stenosis

SpO2 :

pulsoxymetrisch gemessene Sauerstoffsättigung

SWIFT:

Solitaire™ FR With the Intention For Thrombectomy

SYNTHESIS:

Synthesis Expansion: A Randomized Controlled Trial on Intra-Arterial Versus Intravenous Thrombolysis in Acute Ischemic Stroke

TREVO:

Thrombectomy Revascularization of Large Vessel Occlusions in Acute Ischemic Stroke

WASID:

Warfarin-Aspirin Symptomatic Intracranial Disease

ZVK:

zentraler Venenkatheter

Literatur

  1. Abou-Chebl A, Lin R, Hussain MS et al (2010) Conscious sedation versus general anesthesia during endovascular therapy for acute anterior circulation stroke: preliminary results from a retrospective, multicenter study. Stroke 41:1175–1179

    Article  PubMed  CAS  Google Scholar 

  2. Anastasian ZH, Strozyk D, Meyers PM et al (2011) Radiation exposure of the anesthesiologist in the neurointerventional suite. Anesthesiology 114:512–520

    Article  PubMed  Google Scholar 

  3. Berlis A (2006) Endovaskuläre Rekanalisationsverfahren bei der Behandlung des akuten Schlaganfalls. Habilitationsschrift, Albert-Ludwigs-Universität, Freiburg

  4. Berlis A, Lutsep H, Barnwell S et al (2004) Mechanical thrombolysis in acute ischemic stroke with EPAR (endovascular photoacoustic recanalization). Stroke 35:1112–1116

    Article  PubMed  Google Scholar 

  5. Bose A, Alfke K, Henkes H et al (2008) The Penumbra system: a mechanical device for the treatment of acute stroke due to thromboembolism. AJNR Am J Neuroradiol 29:1409–1413

    Article  PubMed  CAS  Google Scholar 

  6. Brekenfeld C, Heinrich P, Mattle H, Schroth G (2010) General is better than local anesthesia during endovascular procedures. Stroke 41:2716–2717

    Article  PubMed  Google Scholar 

  7. Broderick JP, Palesch YY, Demchuk AM et al (2013) Endovascular therapy after intravenous versus t-PA alone for stroke. N Engl J Med 368:893–903

    Article  PubMed  CAS  Google Scholar 

  8. Chimowitz MI, Lynn MJ, Derdeyn CP et al (2011) Stenting versus aggressive medical therapy for intracranial arterial stenosis. N Engl J Med 365:993–1003

    Article  PubMed  CAS  Google Scholar 

  9. Chimowitz MI, Lynn MJ, Howlett-Smith H et al (2005) Comparison of warfarin and aspirin for symptomatic intracranial arterial stenosis. N Engl J Med 352:1305–1316

    Article  PubMed  CAS  Google Scholar 

  10. Ciccone A, Valvassori L, Nichelatti M et al (2013) Endovascular treatment for acute ischemic stroke. N Engl J Med 368:904–913

    Article  PubMed  CAS  Google Scholar 

  11. Coley S, Sneade M, Clarke A et al (2012) Cerecyte coil trial: procedural safety and clinical outcome in patients with ruptured and unruptured intracranial aneurysms. AJNR Am J Neuroradiol 33:474–480

    Article  PubMed  CAS  Google Scholar 

  12. Davis MJ, Menon BK, Baghirzada LB et al (2012) Anesthetic management and outcome in patients during endovascular therapy for acute stroke. Anesthesiology 116:396–405

    Article  PubMed  CAS  Google Scholar 

  13. Dorn F, Stehle S, Lockau H et al (2012) Endovascular treatment of intracerebral artery occlusions with the solitaire stent: single-centre experience with 108 recanalization procedures. Cerebrovasc Dis 34:70–77

    Article  PubMed  CAS  Google Scholar 

  14. Elijovich L, Randall T, Higashida MD et al (2008) Predictors and outcomes of intraprocedural rupture in patients treated for ruptured intracranial aneurysms the CARAT study. Stroke 39:1501–1506

    Article  PubMed  Google Scholar 

  15. Eckert B (2009) Acute stroke therapy 1981–2009. Clin Neuroradiol 1:8–19

    Article  Google Scholar 

  16. Flexman AM, Donavan AL, Gelb AW (2012) Anesthetic management of patients with acute stroke. Anesthesiol Clin 30:175–190

    Article  PubMed  Google Scholar 

  17. Galimanis A, Jung S, Mono M-L et al (2012) Endovascular therapy of 623 patients with anterior circulation stroke. Stroke 43:1052–1057

    Article  PubMed  Google Scholar 

  18. Gugliemi G, Vinuela F, Dion J, Duckwiler G (1991) Electrothrombosis of saccular aneurysms via endovascular approach, part 2. Preliminary clinical results. J Neurosurg 75:8–14

    Article  Google Scholar 

  19. Gugliemi G, Vinuela F, Duckwiler G et al (1992) Endovascular treatment of posterior circulation aneurysms by electrothrombosis using electrically detachable coils. J Neurosurg 77:515–524

    Article  Google Scholar 

  20. Hashimoto T, Gupta DK, Young WL (2002) Interventional neuroradiology – anesthetic consderations. Anesthesiol Clin North America 20:347–359

    Article  PubMed  Google Scholar 

  21. Hassan AE, Chaudhry SA, Zacharatos H et al (2012) Increased risk of aspiration pneumonia and poor discharge outcome among acute ischemic stroke patients following intubation for endovascular treatment. Neurocrit Care 16:246–250

    Article  PubMed  CAS  Google Scholar 

  22. John N, Mitchell P, Dowling R, Yan B (2013) Is general anaesthesia preferable to conscious sedation in the treatment of acute ischaemic stroke with intra-arterial mechanical thrombectomy? A review of the literature. Neuroradiology 55:93–100

    Article  PubMed  CAS  Google Scholar 

  23. Jumaa MA, Zhang F, Ruiz-Ares F (2010) Comparison of safety and clinical and radiographic outcomes in endovascular acute stroke therapy for proximal middle cerebral artery occlusion with intubation and general anesthesia versus non-intubated state. Stroke 41:1180–1184

    Article  PubMed  Google Scholar 

  24. Kidwell CS, Jahan R, Gornbein J et al (2013) A trial of imaging selection and endovascular treatment for ischemic stroke. N Engl J Med 368:914–923

    Article  PubMed  CAS  Google Scholar 

  25. Koh JS, Lee SJ, Ryu C-W, Kim SH (2012) Safety and efficacy of mechanical thrombectomy with solitaire stent retrieval for acut ischemic stroke: a systematic review. Neurointervention 7:1–9

    Article  PubMed  Google Scholar 

  26. Mattle HP, Arnold M, Georgiadis D et al (2008) Comparison of intra-arterial and intravenous thrombolysis for ischemic stroke with hyperdense middle cerebral artery sign (HMCAS). Stroke 39:379–383

    Article  PubMed  Google Scholar 

  27. McDougall CG, Spetzler RF, Zabramski JM et al (2012) The Barrow ruptured aneurysm trial. J Neurosurg 116:135–144

    Article  PubMed  Google Scholar 

  28. Molyneux A, Kerr R, Stratton I et al (2002) International Subarachnoid Aneurysm Trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised trial. Lancet 60:1267–1274

    Article  Google Scholar 

  29. Molyneux AJ, Kerr RS, Birks J et al (2009) Risk of recurrent subarachnoid haemorrhage, death, or dependence and standardised mortality ratios after clipping or coiling of an intracranial aneurysm in the International Subarachnoid Aneurysm Trial (ISAT): long‐term follow‐up. Lancet Neurol 8:427–433

    Article  PubMed  Google Scholar 

  30. Molyneux AJ, Kerr RS, Yu LM et al (2005) International subarachnoid trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised comparison of effects on survival, dependency, seizures, rebleeding, subgroups, and aneurysm occlusion. Lancet 366:809–817

    Article  PubMed  Google Scholar 

  31. Moret J, Cognard C, Weil A et al (1997) Reconstruction technic in the treatment of wide-neck intracranial aneurysm. Long-term angiographic and clinical results. Apropos 56 cases. J Neuroradiol 24:30–44

    PubMed  CAS  Google Scholar 

  32. Nichols C, Carrozella J, Yeatts S (2010) Is periprocedural sedation during acute stroke therapy associated with poorer functional outcomes? J Neurointerv Surg 2:67–70

    Article  PubMed  CAS  Google Scholar 

  33. Nogueira RG, Lutsep HL, Gupta R et al (2012) Trevo versus Merci retrievers for thrombectomy revascularisation of large vessel occlusions in acute ischaemic sroke (TREVO 2): a randomised trial. Lancet 380:1231–1240

    Article  PubMed  Google Scholar 

  34. Pfefferkorn T, Holtmannspötter M, Schmidt C et al (2010) Drip, ship, and retrieve: cooperative recanalization therapy in acute basilar artery occlusion. Stroke 41:722–726

    Article  PubMed  Google Scholar 

  35. Preiß H, Reinartz J, Lowens S, Henkes H (2006) Anästhesiologisches Management bei neuroendovaskulären Eingriffen. Anaesthesist 55:679–692

    Article  PubMed  Google Scholar 

  36. Rha J-H, Saver JL (2007) The impact of recanalization on ischemic stroke outcome: a meta-analysis. Stroke 38:967–973

    Article  PubMed  Google Scholar 

  37. Riedel CH, Jensen U, Rohr A et al (2010) Assesment of thrombus in acute middle cerebral artery occlusion using thin-slice nonenhanced computed tomography reconstructions. Stroke 41:1659–1664

    Article  PubMed  Google Scholar 

  38. Risselada R, Lingsma HF, Bauer-Mehren A et al (2011) Prediction of 60 day case-fatality after aneurysmal subarachnoid haemorrhage: results from the International Subarachnoid Aneurysm Trial (ISAT). Eur J Epidemiol 25:261–266

    Article  Google Scholar 

  39. Sauer H, Wankmüller H, Leschke M (2012) Blutungsmanagement, perioperatives und periprozedurales Bridging. Vorschlag praktischer Strategien für die neuen oralen Antikoagulantien. Klinikarzt 41:26–32

    Article  Google Scholar 

  40. San Roman L, Obach V, Blasco J et al (2012) Single-center experience of cerebral artery thrombectomy using the TREVO device in 60 patients with acute ischemic stroke. Stroke 43:1657–1659

    Article  Google Scholar 

  41. Saver JL, Jahan R, Levy EI et al (2012) Solitaire flow restoration device versus the Merci Retriever in patients with acute ischaemic stroke (SWIFT): a randomised, parallel-group, non-inferority trial. Lancet 380:1241–1249

    Article  PubMed  Google Scholar 

  42. Serbinenko FA (1974) Balloon occlusion of saccular aneurysms of the cerebral arteries. Vopr Neirokhir 4:8–15

    PubMed  Google Scholar 

  43. Scott RB, Eccles F, Molyneux AJ et al (2010) Improved cognitive outcomes with endovascular coiling of ruptured intracranial aneurysms. Neuropsychological outcomes from the International Subarachnoid Aneurysm Trial (ISAT). Stroke 41:1743–1747

    Article  PubMed  Google Scholar 

  44. Smith WS, Sung G, Saver J et al (2008) Mechanical thrombectomy for acute ischemic stroke: final results of the Multi MERCI Trial. Stroke 39:1205–1212

    Article  PubMed  Google Scholar 

  45. Sussmann BJ, Fitch TSP (1958) Thrombolysis with fibrinolysis in cerebral artery occlusion. J Am Med Assoc167:1705–1709

    Google Scholar 

  46. Taschner CA, Treier M, Schumacher M et al (2011) Mechanical thrombectomy with the Penumbra recanalization device in acute ischemic stroke. J Neuroradiol 38:47–52

    Article  PubMed  Google Scholar 

  47. White PM, Lewis SC, Gholkar A, Sellar et al (2011) Hydrogel-coated coils versus bare platinum coils for the endovascualr treatment of intracranial aneurysms (HELPS): a randomized controlled trial. Lancet 377:1655–1662

    Article  PubMed  CAS  Google Scholar 

  48. Yoon W (2011) Current update on the randomized controlled trials of intracranial aneurysms. Neurointervention 6:1–5

    Article  PubMed  Google Scholar 

  49. Young WL, Pile-Spellman J, Hacein-Bey L, Joshi S (1997) Invasive neuroradiologic procedures for cerebrovascular abnormalities: anesthetic considerations. Anethesiol Clin North America 15:631–653

    Article  Google Scholar 

  50. Young WL (2007) Anesthesia for endovascular neurosurgery and interventional neuroradiology. Anesthesiol Clin 25:391–412

    Article  PubMed  CAS  Google Scholar 

  51. Zeumer H, Hacke W, Kolmann HL, Poeck K (1982) Lokale Fibrinolysetherapie bei Basilaris-Thrombose. Dtsch Med Wochenschr 107:728–731

    Article  PubMed  CAS  Google Scholar 

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Danksagung

Herrn Prof. Dr med. Helmuth Forst, Chefarzt für Anästhesie und Intensivmedizin am Klinikum Augsburg, wird für seine stete Bereitschaft zur Diskussion, die bei der Abfassung des Manuskripts hilfreich war, gedankt.

Einhaltung ethischer Richtlinien

Interessenkonflikt. A. Berlis gibt an, dass er zum Zeitpunkt der Abfassung des Manuskripts Beraterverträge mit den Firmen ev3/covidien und Microvention/Terumo besitzt. Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren.

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Berlis, A. Endovaskuläre Eingriffe in der interventionellen Neuroradiologie. Anaesthesist 62, 692–706 (2013). https://doi.org/10.1007/s00101-013-2227-1

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