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Massive symptomatic subependymoma of the lateral ventricles: case report and review of the literature

  • Diagnostic Neuroradiology
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Abstract

Subependymomas are benign intraventricular tumors with an indolent growth pattern, which are usually asymptomatic, and most commonly occur in the fourth and lateral ventricles. When symptomatic, subependymomas often obstruct critical portions of the cerebrospinal fluid (CSF) pathway, causing hydrocephalus, and range from 3 cm to 5 cm in size. We report a case of an unusually massive subependymoma of the lateral ventricles treated with subtotal resection, ventriculoperitoneal shunt, and post-surgical radiation. The clinical course, radiographic and pathologic characteristics of this massive intraventricular subependymoma are discussed, as well as the differential diagnosis of lateral ventricular masses and a review of the literature concerning subependymomas.

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References

  1. Scheinker IM (1945) Subependymoma: a newly recognized tumor of subependymal derivation. J Neurosurg 2:232–240

    Google Scholar 

  2. Scheithauer BW (1978) Symptomatic subependymoma: report of 21 cases with review of the literature. J Neurosurg 49:689–696

    Google Scholar 

  3. Jooma R, Torrens MJ, Bradshaw J, Brownell B (1985) Subependymomas of the fourth ventricle: surgical treatment in 12 cases. J Neurosurg 62:508–512

    Google Scholar 

  4. Artico M, Bardella L, Ciappetta P, Raco A (1989) Surgical treatment of subependymomas of the central nervous system: report of 8 cases and review of the literature. Acta Neurochir 98:25–31

    Google Scholar 

  5. Lombardi D, Scheithauer BW, Meyer FB, Forbes GS, Shaw EG, Gibney DJ, Katzmann JA (1991) Symptomatic subependymoma: a clinicopathological and flow cytometric study. J Neurosurg 75:583–588

    Google Scholar 

  6. Chiechi MV, Smirniotopoulos JG, Jones RV (1995) Intracranial subependymomas: CT and MR imaging features in 24 cases. Am J Roentgenol 165:1245–1250

    CAS  Google Scholar 

  7. Maiuri F, Gangemi M, Iaconetta G, Signorelli F, Del Basso De Caro M (1997) Symptomatic subependymomas of the lateral ventricles. Report of eight cases. Clin Neurol Neurosur 99:17–22

    Article  Google Scholar 

  8. Prayson RA, Suh JH (1999) Subependymomas: clinicopathologic study of 14 tumors, including comparative MIB-1 immunohistochemical analysis with other ependymal neoplasms. Arch Pathol Lab Med 123:306–309

    Google Scholar 

  9. Im SH, Paek SH, Choi YL, Chi JG, Kim DG, Jung HW, Cho BK (2003) Clinicopathological study of seven cases of symptomatic supratentorial subependymoma. J Neuro-Oncol 61:57–67

    Article  Google Scholar 

  10. Koeller KK, Sandberg GD (2002) Cerebral intraventricular neoplasms: radiologic–pathologic correlation. Radiographics 22:1473–1505

    PubMed  Google Scholar 

  11. Matsumara A, Ahyai A, Hori A, Schaake T (1989) Intracerebral subependymomas: clinical and neuropathological analyses with special reference to the possible existence of a less benign variant. Acta Neurochir 96:15–25

    Google Scholar 

  12. Fu Y, Chen AT, Kay S, Young H (1974) Is subependymoma (subependymal glomerate astrocytoma) an astroctyoma or ependymoma? A comparative ultrastructural and tissue culture study. Cancer 34:1992–2008

    Google Scholar 

  13. Azzarelli B, Rekate HL, Roessmann U (1977) Subependymoma: a case report with ultrastructural study. Acta Neuropathol 40:279–282

    Article  Google Scholar 

  14. Moss TH (1984) Observation on the nature of subependymoma: an electron microscopic study. Neuropathol Appl Neurobiol 10:63–75

    Google Scholar 

  15. Friede RL, Pollak A (1978) The cytogenetic basis for classifying ependymomas. J Neuropathol Exp Neurol 37:103–118

    Google Scholar 

  16. Lobato RD, Sarabia M, Castro S, Esparza J, Cordobes F, Portillo JM, Rivas JJ (1986) Symptomatic subependymoma: report of four new cases studied with computed tomography and review of the literature. Neurosurgery 19:594–598

    Google Scholar 

  17. Nishio S, Morioka T, Mihara F, Fukui M (2000) Subependymoma of the lateral ventricles. Neurosurg Rev 23:98–103

    Google Scholar 

  18. Kim DG, Han MH, Lee SH, Chi JG, Cho KJ, Kim JH, Choi KS, Han DH (1993) MRI of intracranial subependymoma: report of a case. Neuroradiology 35:185–186

    CAS  PubMed  Google Scholar 

  19. Hoeffel C, Boukobza M, Polivka M, Lot G, Guichard JP, Lafitte F, Reizine D, Merland JJ (1995) MR manifestations of subependymomas. Am J Neuroradiol 16:2121–2129

    Google Scholar 

  20. Silverstein JE, Lenchik L, Stanciu MG, Shimkin PM (1995) MRI of intracranial subependymomas. J Comput Assist Tomogr 19:264–267

    CAS  PubMed  Google Scholar 

  21. Yamasaki T, Kikuchi H, Higashi T, Yamabe H, Moritake K (1990) Two surgically cured cases of subependymoma with emphasis on magnetic resonance imaging. Surg Neurol 33:329–335

    Article  CAS  PubMed  Google Scholar 

  22. Jelinek J, Smirniotopoulos JG, Parisi JE, Kanzer M (1990) Lateral ventricular neoplasms of the brain: differential diagnosis based on clinical, CT, and MR findings. Am J Roentgenol 155:365–372

    CAS  Google Scholar 

  23. Seol HJ, Hwang SK, Choi YL, Chi JG, Jung HW (2003) A case of recurrent subependymoma with subependymal seeding: case report. J Neuro-Oncol 62: 315–320

    Article  Google Scholar 

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Correspondence to PC Sundgren.

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Rath, T., Sundgren, P., Brahma, B. et al. Massive symptomatic subependymoma of the lateral ventricles: case report and review of the literature. Neuroradiology 47, 183–188 (2005). https://doi.org/10.1007/s00234-005-1342-3

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  • DOI: https://doi.org/10.1007/s00234-005-1342-3

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