Abstract.
A 48-year-old man suddenly developed clinically and electroencephalographically nonspecific dementia. On MRI sequences, only diffusion-weighted images (DWI) of the cortex were unequivocally pathological. Obvious atrophy and basal ganglia signal changes appeared only 9 months after the onset. Brain biopsy confirmed Creutzfeldt-Jakob disease (CJD). In rapidly progressive dementia, we recommend DWI for early diagnosis of CJD.
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Tribl, G., Strasser, G., Zeitlhofer, J. et al. Sequential MRI in a case of Creutzfeldt-Jakob disease. Neuroradiology 44, 223–226 (2002). https://doi.org/10.1007/s002340100695
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DOI: https://doi.org/10.1007/s002340100695