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Duplication of the pituitary gland in a newborn with median cleft face syndrome and nasal teratoma

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Abstract

A newborn suffered immediate neonatal respiratory distress because of an obstructive, soft-tissue nasal mass. Clinical examination revealed a cleft palate with a protruding polypoid mass. CT and MRI showed a heterogeneous nasopharyngeal mass and associated intracranial abnormalities – duplication of the hypophysis and hypoplasia of the corpus callosum. Duplication of the hypophysis is a very rare malformation, only 13 cases having been previously described. The suggested pathogenesis is duplication of the prechordal plate and anterior end of the notochord during early embryological development.

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Received: 12 September 1997 Accepted: 18 September 1997

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Hamon-Kérautret, M., Ares, G., Demondion, X. et al. Duplication of the pituitary gland in a newborn with median cleft face syndrome and nasal teratoma. Pediatric Radiology 28, 290–292 (1998). https://doi.org/10.1007/s002470050354

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  • DOI: https://doi.org/10.1007/s002470050354

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