Abstract
Purpose
To examine the effect of an ultrasound contrast medium (UCM), Infoson, on Doppler examination of stenotic arteries.
Methods
Stenoses were created in the common carotid artery of six piglets, and examined with spectral Doppler and color Doppler imaging during UCM infusion in the left ventricle.
Results
UCM caused a mean increase in recorded maximal systolic and end-diastolic velocities of 5% and 6%, respectively, while blood flow remained constant. Increased spectral intensity with UCM was accompanied by spectral broadening. Reduction of spectral intensity by adjustment of Doppler gain counteracted the velocity effects and the spectral broadening. With color Doppler, UCM caused dose-dependent color artifacts outside the artery. Flow in narrow stenoses could be visualized with UCM.
Conclusion
The effects of UCM on velocity measurements were slight, and were related to changes in spectral intensity. With color Doppler, UCM may facilitate flow detection, but color artifacts may interfere.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Hilpert PL, Mattrey RF, Mitten RM, Peterson T (1989) IV injection of air-filled human albumin microspheres to enhance arterial Doppler signal: A preliminary study in rabbits. AJR 153:613–616
Goldberg BB, Hilpert PL, Burns PN, Liu J-B, Newman LM, Merton DA, Witlin LA (1990) Hepatic tumors: Signal enhancement at Doppler US after intravenous injection of a contrast agent. Radiology 177:713–717
Becher H, Schlief R (1989) Improved sensitivity of color Doppler by SH U 454. Am J Cardiol 64:374–377
Forsberg F, Liu JB, Burns PN, Merton DA, Goldberg BB (1993) Artifacts in ultrasonic contrast agent studies. J Ultrasound Med 13:357–365
Østensen J, Hede R, Myreng Y, Ege T, Holtz E (1992) Intravenous injection of Albunex microspheres causes thromboxane mediated pulmonary hypertension in pigs, but not in monkeys or rabbits. Acta Physiol Scand 144:307–315
Armitage P, Berry G (1987) Statistical Methods in Medical Research. Blackwell Scientific, Oxford, pp 179–185
Pozniak MA, Zagzebski JA, Scanlan KA (1992) Spectral and color Doppler artifacts. RadioGraphics 12:35–44
de Jong N, Ten Cate FJ, Vletter WB, Roelandt JRCT (1993) Quantification of transpulmonary echocontrast effects. Ultrasound Med Biol 19:279–288
Hoff L, Christiansen C, Skotland T (1994) Consideration about the contribution to acoustic backscatter from Albunex microspheres with different sizes. J Ultrasound Med 13:181–182
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Abildgaard, A., Egge, T.S., Kløw, NE. et al. Use of sonicated albumin (infoson) to enhance arterial spectral and color Doppler imaging. Cardiovasc Intervent Radiol 19, 265–271 (1996). https://doi.org/10.1007/BF02577647
Issue Date:
DOI: https://doi.org/10.1007/BF02577647