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Functional magnetic resonance imaging for neurosurgical planning in neurooncology

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Abstract

Functional magnetic resonance imaging (fMRI) is a non-invasive technique that is widely available and can be used to determine the spatial relationships between tumor tissue and eloquent brain areas. Within certain limits, this functional information can be applied in the field of neurosurgery as a pre-operative mapping tool to minimize damage to eloquent brain areas. In this article, we review the literature on the use of fMRI for neurosurgical planning. The issues addressed are: (1) stimulation paradigms, (2) the influence of tumors on the blood oxygenation level-dependent (BOLD) signal, (3) post-processing the fMRI time course, (4) integration of fMRI results into neuronavigation systems, (5) the accuracy of fMRI and (6) fMRI compared to intra-operative mapping (IOM).

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Acknowledgments

The authors thank Cristina Lavini for her help with the implementation fMRI in our hospital, and Wendy van Noppen for her help with the preparation of this manuscript.

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  1. Department of Radiology, Academic Medical Center, P.O. Box 22660, 1100 DD, Amsterdam, The Netherlands

    Erik-Jan Vlieger, Charles B. Majoie & Gerard J. den Heeten

  2. Department of Neurosurgery, Academic Medical Center, 1100 DD, Amsterdam, The Netherlands

    Sieger Leenstra

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  1. Erik-Jan Vlieger
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  2. Charles B. Majoie
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Correspondence to Erik-Jan Vlieger.

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Vlieger, EJ., Majoie, C.B., Leenstra, S. et al. Functional magnetic resonance imaging for neurosurgical planning in neurooncology. Eur Radiol 14, 1143–1153 (2004). https://doi.org/10.1007/s00330-004-2328-y

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