Abstract
The objective was to describe the clinical features and management of cerebral venous thrombosis (CVT) in non-selected centres. An observational study in 11 neurological departments in NW Italy was carried out from 1995 through 1999 on 38 female and 10 male patients. Mean age: 44.8 years, SD=14.3. Onset: acute in 21 patients (44%), subacute in 17 (35%) and chronic in 10 (21%). Most frequent onset: with focal deficits and/or seizures, followed by impaired consciousness or confusion, isolated headache, isolated intracranial hypertension and cavernous syndrome. No risk factor was found in 8 patients (17%). The superior sagittal sinus was involved in 27 patients (56%) and the transverse sinus in 29 (60%). Anticoagulants were used in 45 patients (94%). Rankin Scale score at discharge: 0 (27 patients), 1 (four), 2 (five), 3 (five), 4 (none), 5 (one) and six were dead. Thirteen patients had deep CVT: age, risk factors, neurological signs and outcome differed from cortical CVT (35 patients), although not significantly. Clinical features, risk factors and outcome of CVT patients from non-selected centres are similar to those from specialised centres.
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*The Cerebral Venous Thrombosis Group includes the following (number of patients provided in brackets): R. Rudà, M. De Mattei, DEA Neurologia, ASOS Giovanni Battista, Torino (13); P. Cerrato, E. Verdun, M. Giraudo, Clinica Neurologica I, University of Torino (12); E. Terazzi, D. Mittino, F. Monaco, M. A. Leone, Clinica Neurologica, Ospedale Maggiore della Carità and University of Piemonte Orientale “A. Avogadro”, Novara (6); E. Grasso, P. Gerbino-Promis, UO Neurologia,Ospedale S. Croce e Carle, Cuneo (6); A. Appiotti, UO Neurologia, Ospedale S. Andrea, Vercelli (3); R. Sciolla, P. Gai, Clinica Neurologica, Ospedale S. Luigi Gonzaga, Orbassano (2); E. Bottacchi, UO Neurologia e Neurofisiopatologia, Ospedale Regionale, Aosta (1); C. Labate, UO Neurologia, Ospedale Mauriziano, Torino (1); A. Villani, UO Neurologia, Ospedale S. Biagio, Domodossola (1); E. Pavanelli, UO Neurologia, Ospedale Gradenigo, Torino (1); G. Ferrari, UO Neurologia, Ospedale Civile, Ivrea (1); P. Provera, UO Neurologia, Ospedale S. Antonio Margherita, Tortona (1).
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Terazzi, E., Mittino, D., Rudà, R. et al. Cerebral venous thrombosis: a retrospective multicentre study of 48 patients. Neurol Sci 25, 311–315 (2005). https://doi.org/10.1007/s10072-004-0363-8
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DOI: https://doi.org/10.1007/s10072-004-0363-8