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New concepts in surgery of WHO grade II gliomas: functional brain mapping, connectionism and plasticity – a review

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Summary

Despite a recent literature supporting the impact of surgery on the natural history of low-grade glioma (LGG), the indications of resection still remain a matter of debate, especially because of the frequent location of these tumors within eloquent brain areas – thus with a risk to induce a permanent postoperative deficit. Therefore, since the antagonist nature of this surgery is to perform the most extensive glioma removal possible, while preserving the function and the quality of life, new concepts were recently applied to LGG resection in order to optimize the␣benefit/risk ratio of the surgery.

First, due to the development of functional mapping methods, namely perioperative neurofunctional imaging and intrasurgical direct electrical stimulation, the study of cortical functional organization is currently possible for each patient – in addition to an extensive neuropsychological assessment. Such knowledge is essential because of the inter-individual anatomo-functional variability, increased in tumors due to cerebral plasticity phenomena. Thus, brain mapping enables to envision and perform a resection according to individual functional boundaries.

Second, since LGG invades not only cortical but also subcortical structures, and shows an infiltrative progression along the white matter tracts, new techniques of anatomical tracking and functional mapping of the subcortical white matter pathways were also used with the goal to study the individual effective connectivity – which needs imperatively to be preserved during the resection.

Third, the better understanding of brain plasticity mechanisms, induced both by the slow-growing LGG and by the surgery itself, were equally studied in each patient and applied to the surgical strategy by incorporating individual dynamic potential of reorganization into the operative planning.

The integration of these new concepts of individual functional mapping, connectivity and plastic potential to the surgery of LGG has allowed an extent of surgical indications, an optimization of the quality of resection (neuro-oncological benefit), and a minimization of the risk of sequelae (benefit on the quality of life). In addition, such a strategy has also fundamental applications, since it represents a new door to the connectionism and cerebral plasticity.

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References

  1. Kleihues P, Cavenee W: Pathology and genetics of tumours of the nervous system. In: Kleihues P, Cavenee W (eds) International Agency for Research on Cancer Press, Lyon, 2000

  2. Walker DG, Kaye AH, Low grade glial neoplasmsJ Clin Neurosci 10: 1–13, 2003

    Article  PubMed  Google Scholar 

  3. DeAngelis LM, Brain tumorsN Engl J Med 344: 114–123, 2001

    Article  PubMed  CAS  Google Scholar 

  4. Mandonnet E, Delattre JY, Tanguy ML, Swanson KR, Carpentier AF, Duffau H, Cornu P, Van Effenterre R, Alvord EC Jr, Capelle L: Continuous growth of mean tumor diameter in a subset of grade II gliomas Ann Neurol 53: 524–528, 2003

    Article  PubMed  Google Scholar 

  5. Duffau H, Khalil I, Gatignol P, Denvil D, Capelle L: Surgical removal of corpus callosum infiltrated by low-grade glioma: functional outcome and oncological considerations J Neurosurg 100: 431–437, 2004

    PubMed  Google Scholar 

  6. Giese A, Bjerkvig R, Berens ME, Westphal M, Cost of migration: invasion of malignant gliomas and implications for treatmentJ Clin Oncol21: 1624–1636, 2003

    Article  PubMed  CAS  Google Scholar 

  7. Mandonnet E, Capelle L, Duffau H: Extension of paralimbic low-grade gliomas along subcortical pathways: toward a kinetic classification of locations. In: 54th annual meeting, Congress of Neurological Surgeons, San Francisco, 2004

  8. Wessels PH, Weber WEJ, Raven G, Ramaekers FC, Hopman AH, Twijnstra A: Supratentorial grade II astrocytoma: biological features and clinical course Lancet Neurology 2: 395–403, 2003

    Article  PubMed  Google Scholar 

  9. Cavaliere R, Lopes MB, Schiff D, Low-grade gliomas: an update on pathology and therapyLancet Neurol4: 760–770, 2005

    Article  PubMed  Google Scholar 

  10. Johannesen TB, Langmark F, Lote K, Progress in long-term survival in adult patients with supratentorial low-grade gliomas: a population-based study of 993 patients in whom tumors were diagnosed between 1970 and 1993J Neurosurg99: 854–862, 2003

    PubMed  Google Scholar 

  11. Celli P, Nofrone I, Palma L, Cantore G, Fortuna A: Cerebral oligodendroglioma: prognostic factors and life history Neurosurgery 35: 1018–1034, 1994

    PubMed  CAS  Google Scholar 

  12. Kreth FW, Faist M, Rossner R, Volk B, Ostertag CB: Supratentorial World Health Organization grade 2 astrocytomas and oligoastrocytomas. A new pattern of prognostic factors Cancer 79: 370–379, 1997

    Article  PubMed  CAS  Google Scholar 

  13. Leighton C, Fisher B, Bauman G, Depiero S, Stitt L, MacDonald D, Cairncross G, et al: Supratentorial low grade glioma in adults: an analysis of prognostic factors and timing of radiation J Clin Oncol 15: 1294–1301, 1997

    PubMed  CAS  Google Scholar 

  14. Lote K, Egeland T, Hager B, Stenwig B, Skullerud K, Berg-Johnsen J, Storm-Mathisen I, Hirschberg H: Survival, prognostic factors, and therapeutic efficacy in low-grade glioma: a retrospective study in 379 patients J Clin Oncol 15: 3129–3140, 1997

    PubMed  CAS  Google Scholar 

  15. Piepmeier J, Christopher S, Spencer D, Byrne T, Kim J, Knisel JP, Lacy J, Tsukerman L, Makuch R: Variations in the natural history and survival of patients with supratentorial low-grade astrocytomas Neurosurgery 38:872–878, 1996

    Article  PubMed  CAS  Google Scholar 

  16. Pignatti F, van den Bent M, Curran D, Debruyne C, Sylvester R, Therasse P, Afra D, Cornu P, Bolla M, Vecht C, Karim AB: European Organization for Research and Treatment of Cancer Brain Tumor Cooperative Group; European Organization for Research and Treatment of Cancer Radiotherapy Cooperative Group: Prognostic factors for survival in adult patients with cerebral low-grade glioma J Clin Oncol 20: 2076–2084, 2002

    Article  PubMed  Google Scholar 

  17. Stupp R, Janzer RC, Hegi ME, Villemure JG, Mirimanoff RO: Prognostic factors for low-grade gliomas Semin Oncol 30: 23–28, 2003

    Article  PubMed  CAS  Google Scholar 

  18. Bénard F, Romsa J, Hustinx R, Imaging gliomas with positron emission tomography and single-photon emission computed tomographySemin Nucl Med 33: 148–162, 2003

    Article  PubMed  Google Scholar 

  19. De Witte O, Levivier M, Violon P, Salmon I, Damhaut P, Wikler D Jr, Hildebrand J, Brotchi J, Goldman S: Prognostic value positron emission tomography with [18F]fluoro–2–deoxy-D-glucose in the low-grade glioma Neurosurgery 39: 470–476, 1996

    Article  PubMed  Google Scholar 

  20. De Witte O, Oulad Ben Taib N, Branle F, Rorive S, Brotchi J, Goldman S: Contribution of PET to the management of patients with low-grade glioma Neurochirurgie 50: 468–473, 2004

    PubMed  Google Scholar 

  21. Derlon JM, Chapon F, Noel MH, Khouri S, Benali K, Petit-Taboue MC, Houtteville JP, Chajari MH, Bouvard G: Non-invasive grading of oligodendrogliomas: correlation between in vivo metabolic pattern and histology Eur J Nucl Med 27: 778–787, 2000

    Article  PubMed  CAS  Google Scholar 

  22. Galanaud D, Chinot O, Nicoli F, Confort-Gouny S, Le Fur Y, Barrie-Attarian M, Ranjeva JP, Fuentes S, Viout P, Figarella-Branger D, Cozzone PJ: Use of proton magnetic resonance spectroscopy of the brain to differentiate gliomatosis cerebri from low-grade glioma J Neurosurg 98: 269–27, 2003

    PubMed  Google Scholar 

  23. Kuznetsov YE, Caramanos Z, Antel SB, Preul MC, Leblanc R, Villemure JG, Pokrupa R, Olivier A, Sadikot A, Arnold DL: Proton magnetic resonance spectroscopic imaging can predict length of survival in patients with supratentorial gliomas Neurosurgery 53: 565–576, 2003

    Article  PubMed  Google Scholar 

  24. Minn H, PET and SPECT in low-grade gliomaEur J Radiol56: 171–178, 2005

    Article  PubMed  Google Scholar 

  25. Pirzkall A, Nelson SJ, McKnight TR, Takahashi MM, Li X, Graves EE, Verhey LJ, Wara WW, Larson DA, Sneed PK: Metabolic imaging of low-grade gliomas with three-dimensional magnetic resonance spectroscopy Int J Radiat Oncol Biol Phys 53: 1254–1264, 2002

    Article  PubMed  Google Scholar 

  26. Iwadate Y, Sakaida T, Hiwasa T, Nagai Y, Ishikura H, Takiguchi M, Yamaura A: Molecular classification and survival prediction in human gliomas based on proteome analysis Cancer Res 64: 2496–2501, 2004

    Article  PubMed  CAS  Google Scholar 

  27. Mischel PS, Cloughesy TF, Nelson SF, DNA-microarray analysis of brain cancer: molecular classification for therapyNat Rev Neurosci5: 782–792, 2004

    Article  PubMed  CAS  Google Scholar 

  28. Shai R, Shi T, Kremen TJ, Horvath S, Liau LM, Cloughesy TF, Mischel PS, Nelson SF: Gene expression profiling identifies molecular subtypes of gliomas Oncogene 22: 4918–4923, 2003

    Article  PubMed  CAS  Google Scholar 

  29. Smith JS, Perry A, Borell TJ, Lee HK, Oȁ9Fallon J, Hosek SM, Kimmel D, Yates A, Burger PC, Scheithauer BW, Jenkins RB: Alterations of chromosome arms 1p and 19q as predictors of survival in oligodendrogliomas, astrocytomas, and mixed oligoastrocytomas J Clin Oncol 18: 636–645, 2000

    PubMed  CAS  Google Scholar 

  30. Van den Bent MJ, Looijenga LH, Langenberg K, Dinjens W, Graveland W, Uytdewilligen L, Sillevis Smitt PA, Jenkins RB, Kros JM: Chromosomal anomalies in oligodendroglial tumors are correlated with clinical features Cancer 97: 1276–1284, 2003

    Article  PubMed  Google Scholar 

  31. Jbabdi S, Mandonnet E, Duffau H, Capelle L, Swanson KR, Pelegrini-Issac M, Guillevin R, Benali H: Diffusion tensor imaging allows anisotropic growth simulations of low grade gliomas Mag Reson Med 54: 616–624, 2005

    Article  Google Scholar 

  32. Swanson KR, Bridge C, Murray JD, Alvord EC, Jr, Virtual and real brain tumors: using mathematical modeling to quantify glioma growth and invasionJ Neurol Sci 216: 1–10, 2003

    Article  PubMed  Google Scholar 

  33. Aubert A, Costalat R, Duffau H, Benali H: Modeling of pathophysiological coupling between brain electrical activation, energy metabolism and hemodynamics: insights for the interpretation of intracerebral tumor imaging Acta Biotheor 50: 281–295, 2002

    Article  PubMed  Google Scholar 

  34. Berger MS, Deliganis AV, Dobbins J, Keles GE, The effect of extent of resection on recurrence in patients with low grade cerebral hemisphere gliomasCancer 74: 1784–1791, 1994

    PubMed  CAS  Google Scholar 

  35. Berger MS, Rostomily RC, Low grade gliomasJ Neurooncol34: 85–101, 1997

    Article  PubMed  CAS  Google Scholar 

  36. Capelle L, Duffau H, Lopes M, Sichez JP, Bitar A, Faillot T, Arthuis F, Cornu P, Van Effenterre R, Keime-Guibert F, Carpentier A, Hong-Xuan K, Sanson M, Delattre JY, Kujas M, Mokhtari K, Poirier J, Sahel M, Zouaoui A, Lehericy S, Guillevin R, Guerin G, Mitchell MC, Roche S, Abdennour L, Puybasset L: Who grade 2 gliomas in adults: a study of prognostic factors with special emphasis on the role of surgery J Neurooncol 4: S17–69, 2002

    Google Scholar 

  37. Claus EB, Horlacher A, Hsu L, Schwartz RB, Dello-Iacono D, Talos F, Jolesz FA, Black PM: Survival rates in patients with low-grade glioma after intraoperative magnetic resonance image guidance Cancer 103: 1227–1233, 2005

    Article  PubMed  Google Scholar 

  38. Duffau H, Lopes M, Arthuis F, Bitar A, Sichez JP, Van Effenterre R, Capelle L: Contribution of intraoperative electrical stimulations in surgery of low grade gliomas: a comparative study between two series without (1985–96) and with (1996–2003) functional mapping in the same institution J Neurol Neurosurg Psychiatry 76: 845–851, 2005

    Article  PubMed  CAS  Google Scholar 

  39. Keles GE, Lamborn KR, Berger MS, Low-grade hemispheric gliomas in adults: a critical review of extent of resection as a factor influencing outcomeJ Neurosurg95: 735–745, 2001

    PubMed  CAS  Google Scholar 

  40. Laws ER, Shaffrey ME, Morris A, Anderson FA, Jr, Surgical management of intracranial gliomas-does radical resection improve outcome?Acta Neurochir Suppl 85: 47–53, 2003

    PubMed  CAS  Google Scholar 

  41. Lo SS, Cho KH, Hall WA, Hernandez WL, Kossow RJ, Lee CK, Clark HB: Does the extent of surgery have an impact on the survival of patients who receive postoperative radiation therapy for supratentorial low-grade gliomas? Int J Cancer 96: 71–78, 2001

    Article  PubMed  CAS  Google Scholar 

  42. Nakamura M, Konishi N, Tsunoda S, Nakase H, Tsuzuki T, Aoki H, Sakitani H, Inui T, Sakaki T: Analysis of prognostic and survival factors related to treatment of low-grade astrocytomas in adults Oncology 58: 108–116, 2000

    Article  PubMed  CAS  Google Scholar 

  43. Nicolato A, Gerosa MA, Fina P, Iuzzolino P, Giorgiutti F, Bricolo A: Prognostic factors in low-grade supratentorial astrocytomas: a uni-multivariate statistical analysis in 76 surgically treated adult patients Surg Neurol 44: 208–221, 1995

    Article  PubMed  CAS  Google Scholar 

  44. Peraud A, Ansari H, Bise K, Reulen HJ, Clinical outcome of supratentorial astrocytoma WHO grade IIActa Neurochir (Wien)140: 1213–1222, 1998

    Article  CAS  Google Scholar 

  45. Piepmeier J, Baehring JM, Surgical resection for patients with benign primary brain tumors and low grade gliomasJ Neurooncol69: 55–65, 2004

    Article  PubMed  Google Scholar 

  46. Rostomily RC, Keles GE, Berger MS, Radical surgery in the management of low-grade and high-grade gliomasBaillieres Clin Neurol5: 345–369, 1996

    PubMed  CAS  Google Scholar 

  47. Scerrati M, Roselli R, Iacoangeli M, Pompucci A, Rossi GF: Prognostic factors in low grade (WHO grade II) gliomas of the cerebral hemispheres: the role of surgery J Neurol Neurosurg Psychiatry 61: 291–296, 1996

    PubMed  CAS  Google Scholar 

  48. Schmidt MH, Berger MS, Lamborn KR, Aldape K, McDermott MW, Prados MD, Chang SM: Repeated operations for infiltrative low-grade gliomas without intervening therapy J Neurosurg 98: 1165–1169, 2003

    PubMed  Google Scholar 

  49. Karim AB, Afra D, Cornu P, Bleehan N, Schraub S, De Witte O, Darcel F, Stenning S, Pierart M, Van Glabbeke M: Randomized trial on the efficacy of radiotherapy for cerebral low-grade glioma in the adult: European Organization for Research and Treatment of Cancer Study 22845 with the Medical Research Council study BRO4: an interim analysis Int J Radiat Oncol Biol Phys 52:316–324, 2002

    Article  PubMed  Google Scholar 

  50. van den Bent, Afra D, de Witte O, Ben Hassel M, Schraub S, Hoang-Xuan K, Malmstrom PO, Collette L, Pierart M, Mirimanoff R, Karim AB: EORTC Radiotherapy and Brain Tumor Groups and the UK Medical Research Council: Long-term efficacy of early versus delayed radiotherapy for low-grade astrocytoma and oligodendroglioma in adults: the EORTC 22845 randomised trial Lancet 366: 985–990, 2005

    Article  PubMed  Google Scholar 

  51. Karim AB, Maat B, Hatlevoll R, Menten J, Rutten EH, Thomas DG, Mascarenhas F, Horiot JC, Parvinen LM, van Reijn M, Jager JJ, Fabrini MG, van Alphen AM, Hamers HP, Gaspar L, Noordman E, Pierart M, van Glabbeke M: A randomized trial on dose-response in radiation therapy of low-grade cerebral glioma: European Organization for Research and Treatment of Cancer (EORTC) Study 22844 Int J Radiat Oncol Biol Phys 36:549–556, 1996

    Article  PubMed  CAS  Google Scholar 

  52. Papagikos MA, Shaw EG, Stiebert VW, Lessons learned from randomised clinical trials in adult low grade gliomaLancet Oncol6: 240–244, 2005

    Article  PubMed  Google Scholar 

  53. Shaw E, Arusell R, Scheithauer B, Oȁ9Fallon J, Oȁ9Neill B, Dinapoli R, Nelson D, Earle J, Jones C, Cascino T, Nichols D, Ivnik R, Hellman R, Curran W, Abrams R: Prospective randomized trial of low-versus high-dose radiation therapy in adults with supratentorial low-grade glioma: initial report of a North Central Cancer Treatment Group/Radiation Therapy Oncology Group/Eastern Cooperative Oncology Group Study J Clin Oncol 20: 2267–2276, 2002

    Article  PubMed  CAS  Google Scholar 

  54. Buckner JC, Gesme D Jr, Oȁ9Fallon JR, Hammack JE, Stafford S, Brown PD, Hawkins R, Scheithauer BW, Erickson BJ, Levitt R, Shaw EG, Jenkins R: Phase II trial of procarbazine, lomustine, and vincristine as initial therapy for patients with low-grade oligodendroglioma or oligoastrocytoma: efficacy and associations with chromosomal abnormalities J Clin Oncol 21: 251–255, 2003

    Article  PubMed  CAS  Google Scholar 

  55. Chahlavi A, Kanner A, Peereboom D, Staugaitis SM, Elson P, Barnett G: Impact of chromosome 1p status in response of oligodendroglioma to temozolomide: preliminary results J Neurooncol 61: 267–273, 2003

    Article  PubMed  Google Scholar 

  56. Hoang-Xuan K, Capelle L, Kujas M, Taillibert S, Duffau H, Lejeune J, Polivka M, Criniere E, Marie Y, Mokhtari K, Carpentier AF, Laigle F, Simon JM, Cornu P, Broet P, Sanson M, Delattre JY: Temozolomide as initial treatment for adults with low-grade oligodendrogliomas or oligoastrocytomas and correlation with chromosome 1p deletions J Clin Oncol 22: 3133–3138, 2004

    Article  PubMed  CAS  Google Scholar 

  57. Mason WP, Krol GS, DeAngelis LM, Low-grade oligodendroglioma responds to chemotherapyNeurology 46:203, 1996

    PubMed  CAS  Google Scholar 

  58. Quinn JA, Reardon DA, Friedman AH, Rich JN, Sampson JH, Provenzale JM, McLendon RE, Gururangan S, Bigner DD, Herndon JE 2nd, Avgeropoulos N, Finlay J, Tourt-Uhlig S, Affronti ML, Evans B, Stafford-Fox V, Zaknoen S, Friedman HS: Phase II trial of temozolomide in patients with progressive low-grade glioma J Clin Oncol 21: 646–651, 2003

    Article  PubMed  CAS  Google Scholar 

  59. Pace A, Vidiri A, Galie E, Carosi M, Telera S, Cianciulli AM, Canalini P, Giannarelli D, Jandolo B, Carapella CM: Temozolomide chemotherapy for progressive low-grade glioma: clinical benefits and radiological response Ann Oncol 14: 1722–1726, 2003

    Article  PubMed  CAS  Google Scholar 

  60. Soffietti R, Ruda R, Bradac GB, Schiffer D, PCV chemotherapy for recurrent oligodendrogliomas and oligoastrocytomasNeurosurgery43: 1066–1073, 1998

    Article  PubMed  CAS  Google Scholar 

  61. Stege EM, Kros JM, de Bruin HG, Enting RH, van Heuvel I, Looijenga LH, van der Rijt CD, Smitt PA, van den Bent MJ: Successful treatment of low-grade oligodendroglial tumors with a chemotherapy regimen of procarbazine, lomustine, and vincristine Cancer 103:802–809, 2005

    Article  PubMed  CAS  Google Scholar 

  62. Eyre HJ, Crowley JJ, Townsend JJ, Eltringham JR, Morantz RA, Schulman SF, Quagliana JM, al-Sarraf M: A randomized trial of radiotherapy versus radiotherapy plus CCNU for incompletely resected low-grade gliomas: a Southwest Oncology Group study J Neurosurg 78: 909–914, 1993

    PubMed  CAS  Google Scholar 

  63. Kaye AH, Walker DG, Low grade astrocytomas: controversies in managementJ Clin Neurosci7: 475–483, 2000

    Article  PubMed  CAS  Google Scholar 

  64. Rees JH, Low-grade gliomas in adultsCurr Opin Neurol15: 657–661, 2002

    Article  PubMed  Google Scholar 

  65. van den Bent MJ. Advances in the biology and treatment of oligodendrogliomasCurr Opin Neurol17: 675–80, 2004

    Article  PubMed  Google Scholar 

  66. Taphoorn MJ, Klein M, Cognitive deficits in adult patients with brain tumoursLancet Neurol3: 159–168, 2004

    Article  PubMed  Google Scholar 

  67. Tucha O, Smely C, Preier M, Lange KW, Cognitive deficits before treatment among patients with brain tumorsNeurosurgery47: 324–334, 2000

    Article  PubMed  CAS  Google Scholar 

  68. Gregor A, Cull A, Traynor E, Stewart M, Lander F, Love S: Neuropsychometric evaluation of long-term survivors of adult brain tumours: relationship with tumour and treatment parameters Radiother Oncol 41: 55–59, 1996

    PubMed  CAS  Google Scholar 

  69. Klein M, Heimans JJ, Aaronson NK, van der Ploeg HM, Grit J, Muller M, Postma TJ, Mooij JJ, Boerman RH, Beute GN, Ossenkoppele GJ, van Imhoff GW, Dekker AW, Jolles J, Slotman BJ, Struikmans H, Taphoorn MJ: Effect of radiotherapy and other treatment-related factors on mid-term to long-term cognitive sequelae in low-grade gliomas: a comparative study Lancet 360: 1361–1368, 2002

    Article  PubMed  CAS  Google Scholar 

  70. North CA, North RB, Epstein JA, Piantadosi S, Wharam MD: Low-grade cerebral astrocytomas. Survival and quality of life after radiation therapy Cancer 66: 6–14, 1990

    PubMed  CAS  Google Scholar 

  71. Taphoorn MJ, Heimans JJ, Snoek FJ, Lindeboom J, Oosterink B, Wolbers JG, Karim AB: Assessment of quality of life in patients treated for low-grade glioma: a preliminary report J Neurol Neurosurg Psychiatry 55: 372–376, 1992

    PubMed  CAS  Google Scholar 

  72. Taphoorn MJ, Schiphorst AK, Snoek FJ, Lindeboom J, Wolbers JG, Karim AB, Huijgens PC, Heimans JJ: Cognitive functions and quality of life in patients with low-grade gliomas: the impact of radiotherapy Ann Neurol 36: 48–54, 1994

    Article  PubMed  CAS  Google Scholar 

  73. Kiebert GM, Curran D, Aaronson NK, Bolla M, Menten J, Rutten EH, Nordman E, Silvestre ME, Pierart M, Karim AB: Quality of life after radiation therapy of cerebral low-grade gliomas of the adult: results of a randomised phase III trial on dose response (EORTC trial 22844) Eur J Cancer 34: 1902–1909, 1998

    Article  PubMed  CAS  Google Scholar 

  74. Taphoorn MJ: Neurocognitive sequelae in the treatment of low-grade gliomas. Semin Oncol 30: 45–48, 2003

    Google Scholar 

  75. Brown PD, Buckner JC, Oȁ9Fallon JR, Iturria NL, Brown CA, Oȁ9Neill BP, Scheithauer BW, Dinapoli RP, Arusell RM, Curran WJ, Abrams R, Shaw EG: Effects of radiotherapy on cognitive function in patients with low-grade glioma measured by the Folstein Mini-Mental State Examination J Clin Oncol 21: 2519–2524, 2003

    Article  PubMed  Google Scholar 

  76. Brown PD, Buckner JC, Oȁ9Fallon JR, Iturria NL, Oȁ9Neill BP, Brown CA, Scheithauer BW, Dinapoli RP, Arusell RM, Curran WJ, Abrams R, Shaw EG: North Central Cancer Treatment Group; Mayo Clinic: Importance of baseline mini-mental state examination as a prognostic factor for patients with low-grade glioma Int J Radiat Oncol Biol Phys 59: 117–125, 2004

    Article  PubMed  Google Scholar 

  77. Klein M, Heimans JJ, The measurement of cognitive functioning in low-grade glioma patients after radiotherapyJ Clin Oncol22: 966–967, 2004

    Article  PubMed  Google Scholar 

  78. Laack NN, Brown PD, Ivnik RJ, Furth AF, Ballman KV, Hammack JE, Arusell RM, Shaw EG, Buckner JC: North Central Cancer Treatment Group: Cognitive function after radiotherapy for supratentorial low-grade glioma: a north central cancer treatment group prospective study Int J Radiat Oncol Biol Phys 63: 1175–1183, 2005

    Article  PubMed  Google Scholar 

  79. Goldstein B, Obrzut JE, John C, Hunter JV, Armstrong CL: The impact of low-grade brain tumors on verbal fluency performance J Clin Exp Neuropsychol 26: 750–758, 2004

    PubMed  Google Scholar 

  80. Goldstein B, Armstrong CL, Modestino E, Ledakis G, John C, Hunter JV: The impact of left and right intracranial tumors on picture and word recognition memory Brain Cogn 54:1–6, 2004

    Article  PubMed  Google Scholar 

  81. Goldstein B, Armstrong CL, John C, Tallent EM, Attention in adult intracranial tumors patientsJ Clin Exp Neuropsychol25: 66–78, 2003

    PubMed  Google Scholar 

  82. Goldstein B, Obrzut JE, John C, Ledakis G, Armstrong CL: The impact of frontal and non-frontal brain tumor lesions on Wisconsin Card Sorting Test performance Brain Cogn 54: 110–116, 2004

    Article  PubMed  Google Scholar 

  83. Teixidor P, Gatignol P, Leroy M, Masuet-Aumatell C, Capelle L, Duffau H: Assessment of verbal working memory before and after surgery for low-grade glioma. Société de Neurochirurgie de Langue Française, Paris, 2005

    Google Scholar 

  84. Baddeley A, Working memory: looking back and looking forwardNat Rev Neurosci4: 829–839, 2003

    Article  PubMed  CAS  Google Scholar 

  85. Klein M, Engelberts NH, van der Ploeg HM, Kasteleijn-Nolst Trenite DG, Aaronson NK, Taphoorn MJ, Baaijen H, Vandertop WP, Muller M, Postma TJ, Heimans JJ: Epilepsy in low-grade gliomas: the impact on cognitive function and quality of life Ann Neurol 54: 514–520, 2003

    Article  PubMed  Google Scholar 

  86. Andrewes DG, Kaye A, Murphy M, Harris B, Aitken S, Parr C, Bates L: Emotional and social dysfunction in patients following surgical treatment for brain tumor J Clin Neurosci 10: 428–433, 2003

    Article  PubMed  Google Scholar 

  87. Andrewes DG, Kaye A, Aitken S, Parr C, Bates L, Murphy M: The ESDQ: a new method of assessing emotional and social dysfunction in patients following brain surgery J Clin Exp Neuropsychol 25:173–189, 2003

    PubMed  Google Scholar 

  88. Armstrong CL, Hunter JV, Ledakis GE, Cohen B, Tallent EM, Goldstein BH, Tochner Z, Lustig R, Judy KD, Pruitt A, Mollman JE, Stanczak EM, Jo MY, Than TL, Phillips P: Late cognitive and radiographic changes related to radiotherapy: initial prospective findings Neurology 59: 40–48, 2002

    PubMed  CAS  Google Scholar 

  89. Laack NN, Brown PD, Cognitive sequelae of brain radiation in adultsSemin Oncol 31:702–713, 2004

    Article  PubMed  Google Scholar 

  90. Brown PD, Buckner JC, Uhm JH, Shaw EG, The neurocognitive effects of radiation in adult low-grade glioma patientsNeurooncol5: 161–167, 2003

    Google Scholar 

  91. Heimans JJ, Taphoorn MJ, Impact of brain tumour treatment on quality of lifeJ Neurol 249:955–960, 2002

    Article  PubMed  Google Scholar 

  92. Klein M, Heimans JJ, Aaronson NK, Postma TJ, Muller M, van der Ploeg HM, Taphoorn MJ: Impaired cognitive functioning in low-grade glioma patients: relationship to tumor localisation, radiotherapy and the use of anticonvulsants Ned Tijdschr Geneeskd 30;148: 2175–2180, 2004

    Google Scholar 

  93. Postma TJ, Klein M, Verstappen CC, Bromberg JE, Swennen M, Langendijk JA, Taphoorn MJ, Scheltens P, Slotman BJ, van der Ploeg HM, Aaronson NK, Heimans JJ: Radiotherapy-induced cerebral abnormalities in patients with low-grade glioma Neurology 59: 121–123, 2002

    PubMed  CAS  Google Scholar 

  94. Pringle AM, Taylor R, Whittle IR, Anxiety and depression in patients with an intracranial neoplasm before and after tumour surgeryBr J Neurosurg13: 46–51, 1999

    Article  PubMed  CAS  Google Scholar 

  95. Reijneveld JC, Sitskoorn MM, Klein M, Nuyen J, Taphoorn MJ: Cognitive status and quality of life in patients with suspected versus proven low-grade gliomas Neurology 56: 618–623, 2001

    PubMed  CAS  Google Scholar 

  96. Scheibel RS, Meyers CA, Levin VA, Cognitive dysfunction following surgery for intracerebral glioma: influence of histopathology, lesion location, and treatmentJ Neurooncol30: 61–69, 1996

    Article  PubMed  CAS  Google Scholar 

  97. Surma-aho O, Niemela M, Vilkki J, Kouri M, Brander A, Salonen O, Paetau A, Kallio M, Pyykkonen J, Jaaskelainen J: Adverse long-term effects of brain radiotherapy in adult low-grade glioma patients Neurology 56: 1285–1290, 2001

    PubMed  CAS  Google Scholar 

  98. Swennen MH, Bromberg JE, Witkamp TD, Terhaard CH, Postma TJ, Taphoorn MJ: Delayed radiation toxicity after focal or whole brain radiotherapy for low-grade glioma J Neurooncol 66: 333–339, 2004

    Article  PubMed  CAS  Google Scholar 

  99. Torres IJ, Mundt AJ, Sweeney PJ, Llanes-Macy S, Dunaway L, Castillo M, Macdonald RL: A longitudinal neuropsychological study of partial brain radiation in adults with brain tumors Neurology 60: 113–118, 2003

    Article  PubMed  CAS  Google Scholar 

  100. Vigliani MC, Sichez N, Poisson M, Delattre JY, A prospective study of cognitive functions following conventional radiotherapy for supratentorial gliomas in young adults: 4-year resultsInt J Radiat Oncol Biol Phys35: 527–533, 1996

    Article  PubMed  CAS  Google Scholar 

  101. Duffau H, Lessons from brain mapping in surgery for low-grade glioma: insights into associations between tumour and brain plasticityLancet Neurol4: 476–486, 2005

    Article  PubMed  Google Scholar 

  102. Armstrong CL, Goldstein B, Shera D, Ledakis GE, Tallent EM: The predictive value of longitudinal neuropsychologic assessment in the early detection of brain tumor recurrence Cancer 97: 649–656, 2003

    Article  PubMed  Google Scholar 

  103. Duffau H, Capelle L, Denvil D, Sichez N, Gatignol P, Lopes M, Mitchell MC, Sichez JP, Van Effenterre R: Functional recovery after surgical resection of low grade gliomas in eloquent brain: hypothesis of brain compensation J Neurol Neurosurg Psychiatry 74:901–907, 2003

    Article  PubMed  CAS  Google Scholar 

  104. Duffau L, Capelle L, Preferential brain locations of low-grade gliomasCancer 100: 2622–2626, 2004

    Article  PubMed  Google Scholar 

  105. Augustine JR, Circuitry and functional aspects of the insular lobe in primates including humansBrain Res Brain Res Rev22: 229–244, 1996

    Article  PubMed  CAS  Google Scholar 

  106. Zilles K, Schlaug G, Geyer S, Luppino G, Matelli M, Qu M, Schleicher A, Schormann T: Anatomy and transmitter receptors of the supplementary motor areas in the human and nonhuman primate brain Adv Neurol 70: 29–43, 1996

    PubMed  CAS  Google Scholar 

  107. Rivier F, Clarke S, Cytochrome oxidase, acetylcholinesterase, and NADPH-diaphorase staining in human supratemporal and insula cortex: evidence for multiple auditory areas NeuroImage6: 288–304, 1997

    Article  PubMed  CAS  Google Scholar 

  108. Krainik A, Lehericy S, Duffau H, Vlaicu M, Poupon F, Capelle L, Cornu P, Clemenceau S, Sahel M, Valery CA, Boch AL, Mangin JF, Bihan DL, Marsault C: Role of the supplementary motor area in motor deficit following medial frontal lobe surgery Neurology 57: 871–878, 2001

    PubMed  CAS  Google Scholar 

  109. Dronkers NF, A new brain region for coordinating speech articulationNature384: 159–161, 1996

    Article  PubMed  CAS  Google Scholar 

  110. Hatten ME, New directions in neuronal migrationScience297: 1660–1663, 2002

    Article  PubMed  CAS  Google Scholar 

  111. Rakic P, Molecular and cellular mechanisms of neuronal migration: relevance to cortical epilepsiesAdv Neurol84:1–13, 2000

    PubMed  CAS  Google Scholar 

  112. Baumgartner C, Flint R, Tuxhorn I, Van Ness PC, Kosalko J, Olbrich A, Almer G, Novak K, Luders HO: Supplementary motor area seizures: propagation pathways as studied with invasive recordings Neurology 46: 508–514, 1996

    PubMed  CAS  Google Scholar 

  113. Isnard J, Guenot M, Ostrowsky K, Sindou M, Mauguiere F: The role of the insular cortex in temporal lobe epilepsy Ann Neurol 48: 614–623, 2000

    Article  PubMed  CAS  Google Scholar 

  114. Fields RD, Stevens-Graham B, New insights into neuron-glia communicationScience298: 556–562, 2002

    Article  PubMed  CAS  Google Scholar 

  115. Ullian EM, Sapperstein SK, Christopherson KS, Barres BA: Control of synapse number by glia Science 291:657–661, 2001

    Article  PubMed  CAS  Google Scholar 

  116. Apuzzo MLJ, 1993 Brain Surgery. Complication avoidance and Management1Churchill LivingstoneNew York, 379–390

    Google Scholar 

  117. Brell M, Ibanez J, Caral L, Ferrer E: Factors influencing surgical complications of intra-axial brain tumours Acta Neurochir (Wien) 142: 739–750, 2000

    Article  CAS  Google Scholar 

  118. Cabantog AM, Berstein M, Complications of first craniotomy for intra-axial brain tumour Can J Neurol Sci21: 213–218, 1994

    PubMed  CAS  Google Scholar 

  119. Cedzich C, Taniguchi M, Schäfer S, Schramm J: Somatosensory evoked potential phase reversal and direct motor cortex stimulation during surgery in and around the central region. Technical application Neurosurgery 38: 962–971, 1996

    Article  PubMed  CAS  Google Scholar 

  120. Fadul C, Wood J, Thaler H, Galicich J, Patterson RH Jr, Posner JB: Morbidity and mortality of craniotomy for excision of supratentorial gliomas Neurology 38: 1374–1379, 1988

    PubMed  CAS  Google Scholar 

  121. Sawaya R, Hammoud M, Schoppa D, Hess KR, Wu SZ, Shi WM, Wildrick DM: Neurological outcomes in a modern series of 400 craniotomies for treatment of parenchymal tumors Neurosurgery 42: 1044–1056, 1998

    Article  PubMed  CAS  Google Scholar 

  122. Tandon P, Mahapatra AK, Khosla A, Operations on gliomas involving speech centres Acta Neurochir Suppl (Wien)56: 67–71, 1993

    CAS  Google Scholar 

  123. Vives KP, Piepmeier JM, Complications and expected outcome of glioma surgeryJ Neurooncol42: 289–302, 1999

    Article  PubMed  CAS  Google Scholar 

  124. Meyer PT, Sturz L, Schreckenberger M, Spetzger U, Meyer GF, Setani KS, Sabri O, Buell U: Preoperative mapping of cortical language areas in adult brain tumor patients using PET and individual non-normalised SPM analyses Eur J Nucl Med Mol Imaging 30: 951–960, 2003

    Article  PubMed  Google Scholar 

  125. Schreckenberger M, Spetzger U, Sabri O, Meyer PT, Zeggel T, Zimny M, Gilsbach J, Buell U: Localisation of motor areas in brain tumour patients: a comparison of preoperative [18F]FDG-PET and intraoperative cortical electrostimulation Eur J Nucl Med 28: 1394–1403, 2001

    Article  PubMed  CAS  Google Scholar 

  126. Hirsch J, Ruge MI, Kim KH, Correa DD, Victor JD, Relkin NR, Labar DR, Krol G, Bilsky MH, Souweidane MM, DeAngelis LM, Gutin PH: An integrated functional magnetic resonance imaging procedure for preoperative mapping of cortical areas associated with tactile, motor, language and visual functions Neurosurgery 47: 711–722, 2000

    Article  PubMed  CAS  Google Scholar 

  127. Bogomolny DL, Petrovich NM, Hou BL, Peck KK, Kim MJ, Holodny AI: Functional MRI in the brain tumor patient Top Magn Reson Imaging 15: 325–235, 2004

    Article  PubMed  Google Scholar 

  128. Vlieger EJ, Majoie CB, Leenstra S, den Heeten GJ, Functional magnetic resonance imaging for neurosurgical planning in neurooncologyEur Radiol14: 1143–1153, 2004

    Article  PubMed  Google Scholar 

  129. Ganslandt O, Fahlbusch R, Nimsky C, Kober H, Moller M, Steinmeier R, Romstock J, Vieth J: Functional neuronavigation with magnetoencephalography: outcome in 50 patients with lesions around the motor cortex J Neurosurg 91: 73–79, 1999

    PubMed  CAS  Google Scholar 

  130. Schiffbauer H, Berger MS, Ferrari P, Freudenstein D, Rowley HA, Roberts TP: Preoperative magnetic source imaging for brain tumor surgery: a quantitative comparison with intraoperative sensory and motor mapping J Neurosurg 97: 1333–1342, 2002

    PubMed  Google Scholar 

  131. Ganslandt O, Buchfelder M, Hastreiter P, Grummich P, Fahlbusch R, Nimsky C: Magnetic source imaging supports clinical decision making in glioma patients Clin Neurol Neurosurg 107: 20–26, 2004

    Article  PubMed  CAS  Google Scholar 

  132. Lehéricy S, Duffau H, Cornu P, Capelle L, Pidoux B, Carpentier A, Auliac S, Clemenceau S, Sichez JP, Bitar A, Valery CA, Van Effenterre R, Faillot T, Srour A, Fohanno D, Philippon J, Le Bihan D, Marsault C: Correspondence between functional magnetic resonance imaging somatotopy and individual brain anatomy of the central region: comparison with intraoperative stimulation in patients with brain tumors J Neurosurg 92: 589–598, 2000

    PubMed  Google Scholar 

  133. Roux FE, Boulanouar K, Lotterie JA, Mejdoubi M, LeSage JP, Berry I: Language functional magnetic resonance imaging in preoperative assessment of language areas: correlation with direct cortical stimulation Neurosurgery 52: 1335–1345, 2003

    Article  PubMed  Google Scholar 

  134. Petrovich N, Holodny AI, Tabar V, Correa DD, Hirsch J, Gutin PH, Brennan CW: Discordance between functional magnetic resonance imaging during silent speech tasks and intraoperative speech arrest J Neurosurg 103:267–274, 2005

    PubMed  Google Scholar 

  135. Rutten GJ, Ramsey NF, van Rijen PC, Noordmans HJ, van Veelen CW: Development of a functional magnetic resonance imaging protocol for intraoperative localization of critical temporoparietal language areas Ann Neurol 51: 350–360, 2002

    Article  PubMed  CAS  Google Scholar 

  136. Holodny AI, Schulder M, Liu WC, Wolko J, Maldjian JA, Kalnin AJ: The effect of brain tumors on BOLD functional MR Imaging activation in the adjacent motor cortex: implications for image-guided neurosurgery Am J Neuroradiol 21: 1415–1422, 2000

    PubMed  CAS  Google Scholar 

  137. Sobottka SB, Bredow J, Beuthien-Baumann B, Reiss G, Schackert G, Steinmeier R: Comparison of functional brain PET images and intraoperative brain-mapping data using image-guided surgery Comput Aided Surg 7: 317–325, 2002

    Article  PubMed  CAS  Google Scholar 

  138. Rutten GJ, Ramsey N, Noordmans HJ, Willems P, van Rijen P, Berkelbach van der Sprenkel JW, Viergever M, van Veelen C: Toward functional neuronavigation: implementation of functional magnetic resonance imaging data in a surgical guidance system for intraoperative identification of motor and language cortices. Technical note and illustrative case Neurosurg Focus 15: E6, 2003

    PubMed  Google Scholar 

  139. Firsching R, Bondar I, Heinze HJ, Hinrichs H, Hagner T, Heinrich J, Belau A: Practicability of magnetoencephalography-guided neuronavigation Neurosurg Rev 25: 73–78, 2002

    Article  PubMed  CAS  Google Scholar 

  140. Sabbah P, Foehrenbach H, Dutertre G, Nioche C, DeDreuille O, Bellegou N, Mangin JF, Leveque C, Faillot T, Gaillard JF, Desgeorges M, Cordoliani YS: Multimodal anatomic, functional and metabolic brain imaging for tumor resection Clin Imaging 26: 6–12, 2002

    Article  PubMed  CAS  Google Scholar 

  141. Nimsky C, Ganslandt O, Fahlbusch R, Functional neuronavigation and intraoperative MRI Adv Tech Stand Neurosurg29: 229–263, 2004

    PubMed  CAS  Google Scholar 

  142. Dorward NL, Alberti O, Palmer JD, Kitchen ND, Thomas DG: Accuracy of true frameless stereotaxy: in vivo measurement and laboratory phantom studies J Neurosurg 90: 160–168, 1999

    PubMed  CAS  Google Scholar 

  143. Reinges MH, Nguyen HH, Krings T, Hutter BO, Rohde V, Gilsbach JM: Course of brain shift during microsurgical resection of supratentorial cerebral lesions: limits of conventional neuronavigation Acta Neurochir (Wien) 146: 369–377, 2004

    Article  CAS  Google Scholar 

  144. Keles GE, Lamborn KR, Berger MS, Coregistration accuracy and detection of brain shift using intraoperative sononavigation during resection of hemispheric tumorsNeurosurgery53: 556–564, 2003

    Article  PubMed  Google Scholar 

  145. Platenik LA, Miga MI, Roberts DW, Lunn KE, Kennedy FE, Hartov A, Paulsen KD: In vivo quantification of retraction deformation modeling for updated image-guidance during neurosurgery IEEE Trans Biomed Eng 49: 823–835, 2002

    Article  PubMed  Google Scholar 

  146. Keles GE, Intracranial neuronavigation with intraoperative magnetic resonance imaging Curr Opin Neurol17: 497–500, 2004

    Article  PubMed  Google Scholar 

  147. Bradley WG, Achieving gross total resection of brain tumors: intraoperative MR imaging can make a big differenceAm J Neuroradiol23: 348–349, 2002

    PubMed  Google Scholar 

  148. Romstöck J, Fahlbusch R, Ganslandt O, Nimsky C, Strauss C: Localisation of the sensorimotor cortex during surgery for brain tumours: feasibility and waveform patterns of somatosensory evoked potentials J Neurol Neurosurg Psychiatry 72: 221–229, 2002

    Article  PubMed  Google Scholar 

  149. Cedzich C, Taniguchi M, Schäfer S, Schramm J, Somatosensory evoked potential phase reversal and direct motor cortex stimulation during surgery in and around the central region. Technical applicationNeurosurgery38: 962–971, 1996

    Article  PubMed  CAS  Google Scholar 

  150. Wiedemayer H, Sandalcioglu IE, Armbruster W, Regel J, Schaefer H, Stolke D: False negative findings in intraoperative SEP monitoring: analysis of 658 consecutive neurosurgical cases and review of published reports J Neurol Neurosurg Psychiatry 75: 280–286, 2004

    PubMed  CAS  Google Scholar 

  151. Neuloh G, Schramm J, Motor evoked potential monitoring for the surgery of brain tumours and vascular malformationsAdv Tech Stand Neurosurg29: 171–228, 2004

    PubMed  CAS  Google Scholar 

  152. Kombos T, Suess O, Ciklatekerlio O, Brock M, Monitoring of intraoperative motor evoked potentials to increase the safety of surgery in and around the motor cortexJ Neurosurg95: 608–614, 2001

    PubMed  CAS  Google Scholar 

  153. Ikeda A, Miyamoto S, Shibasaki H, Cortical motor mapping in epilepsy patients: information from subdural electrodes in presurgical evaluationEpilepsia43: 56–60, 2002

    Article  PubMed  Google Scholar 

  154. Schaffler L, Lüders HO, Beck GJ, Quantitative comparison of language deficits produced by extraoperative electrical stimulation of Brocaȁ9s, Wernickeȁ9s, and basal temporal language areas Epilepsia37: 463–475, 1996

    Article  PubMed  CAS  Google Scholar 

  155. Chitoku S, Otsubo H, Harada Y, Jay V, Rutka JT, Weiss SK, Abdoll M, Snead OC 3rd: Extraoperative cortical stimulation of motor function in children. Pediatr Neurol 24:344–350, 2001

    Article  PubMed  CAS  Google Scholar 

  156. Crone NE, Functional mapping with ECoG spectral analysisAdv Neurol84: 343–351, 2000

    PubMed  CAS  Google Scholar 

  157. Matsumoto R, Nair DR, LaPresto E, Najm I, Bingaman W, Shibasaki H, Luders HO: Functional connectivity in the human language system: a cortico-cortical evoked potential study Brain 127: 2316–2330, 2004

    Article  PubMed  Google Scholar 

  158. Onal C, Otsubo H, Araki T, Chitoku S, Ochi A, Weiss S, Elliott I, Snead OC 3rd, Rutka JT, Logan W: Complications of invasive subdural grid monitoring in children with epilepsyJ Neurosurg 98: 1017–1026, 2003

    PubMed  Google Scholar 

  159. Berger MS, Ojemann GA, Lettich E, Neurophysiological monitoring during astrocytoma surgeryNeurosurg Clin N Am1: 65–70, 1990

    PubMed  CAS  Google Scholar 

  160. Black PM, Ronner SF, Cortical mapping for defining the limits of tumor resection Neurosurgery25: 786–792, 1987

    Google Scholar 

  161. Danks RA, Rogers M, Aglio LS, Gugino LD, Black PM: Patient tolerance of craniotomy performed with the patient under local anesthesia and monitored conscious sedation Neurosurgery 42: 28–36, 1998

    Article  PubMed  CAS  Google Scholar 

  162. Danks RA, Aglio LS, Gugino LD, Black PM, Craniotomy under local anesthesia and monitored conscious sedation for the resection of tumors involving eloquent cortexJ Neurooncol49:131–139, 2000

    Article  PubMed  CAS  Google Scholar 

  163. Duffau H, Capelle L, Sichez J, Faillot T, Abdennour L, Law Koune JD, Dadoun S, Bitar A, Arthuis F, Van Effenterre R, Fohanno D: Intraoperative direct electrical stimulations of the central nervous system: the Salpêtrière experience with 60 patients Acta Neurochir (Wien) 141:1157–1167, 1999

    Article  CAS  Google Scholar 

  164. Ebel H, Ebel M, Schillinger G, Klimek M, Sobesky J, Klug N: Surgery of intrinsic cerebral neoplasms in eloquent areas under local anesthesia Minim Invasive Neurosurg 43: 192–196, 2000

    Article  PubMed  CAS  Google Scholar 

  165. Ebeling U, Schmid UD, Ying H, Reulen HJ, Safe surgery of lesions near the motor cortex using intraoperative mapping techniques: a report on 50 patientsActa Neurochir (Wien)119: 23–28, 1992

    Article  CAS  Google Scholar 

  166. Fukaya C, Katayama Y, Yoshino A, Kobayashi K, Kasai M, Yamamoto T: Intraoperative wake-up procedure with propofol and laryngeal mask for optimal excision of brain tumor in eloquent areas J Clin Neurosci 8:253–255, 2001

    Article  PubMed  CAS  Google Scholar 

  167. Horstmann GA, Talies S, Westermann B, Reinhardt HF, Microstereometrically guided cortical stimulation for the intraoperative identification of the central motor stripStereotact Funct Neurosurg65: 130–135, 1995

    PubMed  CAS  Google Scholar 

  168. Krombach GA, Spetzger U, Rohde V, Gilsbach JM, Intraoperative localization of functional regions in the sensorimotor cortex by neuronavigation and cortical mappingComput Aided Surg32: 64–73, 1998

    Article  Google Scholar 

  169. Lanier WL, Brain tumor resection in the awake patientMayo Clin Proc76: 677–687, 2001

    PubMed  Google Scholar 

  170. Lumenta CB, Gumprecht HK, Leonardi MA, Gerstner W, Brehm B: Three-dimensional computer-assisted stereotactic-guided microneurosurgery combined with cortical mapping of the motor area by direct electrostimulation Minim Invasive Neurosurg 40: 50–54, 1997

    PubMed  CAS  Google Scholar 

  171. Manninen PH, Tan TK, Postoperative nausea and vomiting after craniotomy for tumor surgery: a comparison between awake craniotomy and general anesthesiaJ Clin Anesth14: 279–283, 2002

    Article  PubMed  Google Scholar 

  172. Meyer FB, Bates LM, Goerss SJ, Friedman JA, Windschitl WL, Duffy JR, Perkins WJ, Oȁ9Neill BP: Awake craniotomy for aggressive resection of primary gliomas located in eloquent brain Mayo Clin Proc 76: 677–687, 2001

    PubMed  CAS  Google Scholar 

  173. Nikas DC, Danks RA, Black PM, 2001 Tumor surgery under local anesthesia. In Loftus CM, Batjer HH, (eds). Techniques in Neurosurgery7Lippincott Williams & Wilkins Philadelphia, 70–84

    Google Scholar 

  174. Peraud A, Meschede M, Eisner W, Ilmberger J, Reulen HJ: Surgical resection of grade II astrocytomas in the superior frontal gyrus Neurosurgery 50: 966–977, 2002

    Article  PubMed  Google Scholar 

  175. Peraud A, Ilmberger J, Reulen HJ, Surgical resection of gliomas WHO grade II and III located in the opercular regionActa Neurochir (Wien)146: 9–17, 2004

    Article  CAS  Google Scholar 

  176. Reithmeier T, Krammer M, Gumprecht H, Gerstner W, Lumenta CB: Neuronavigation combined with electrophysiological monitoring for surgery of lesions in eloquent brain areas in 42 cases: a retrospective comparison of the neurological outcome and the quality of resection with a control group with similar lesions Minim Invasive Neurosurg 46: 65–71, 2003

    Article  PubMed  CAS  Google Scholar 

  177. Reulen HJ, Schmid UD, Ilmberger J, Eisner W, Bise K: Tumor surgery of the speech cortex in local anesthesia. Neuropsychological and neurophysiological monitoring during operations in the dominant hemisphere Nervenarzt 68: 813–824, 1997

    Article  PubMed  CAS  Google Scholar 

  178. Sarang A, Dinsmore J, Anesthesia for awake craniotomy – evolution of a technique that facilitates awake neurological testingBr J Anaesth90: 161–165, 2003

    Article  PubMed  CAS  Google Scholar 

  179. Signorelli F, Guyotat J, Isnard J, Schneider F, Mohammedi R, Bret P: The value of cortical stimulations applied to the surgery of malignant gliomas in language areas Neurol Sci 22: 3–10, 2001

    Article  PubMed  CAS  Google Scholar 

  180. Signorelli F, Guyotat J, Mottolese C, Schneider F, Dȁ9Acunzi G, Isnard J: Intraoperative electrical stimulation mapping as an aid for surgery of intracranial lesions involving motor areas in children Childs Nerv Syst 20: 420–426, 2004

    Article  PubMed  Google Scholar 

  181. Suess O, Kombos T, Hoell T, Baur S, Pietilae T, Brock M: A new cortical electrode for neuronavigation-guided intraoperative neurophysiological monitoring: technical note Acta Neurochir (Wien) 142: 329–332, 2000

    Article  CAS  Google Scholar 

  182. Taylor MD, Bernstein M, Awake craniotomy with brain mapping as a routine surgical approach to treating patients with supratentorial intraaxial tumors: a prospective trial of 200 casesJ Neurosurg90: 35–41, 1999

    PubMed  CAS  Google Scholar 

  183. Wagner W, Tschiltschke W, Niendorf WR, Schroeder HW, Gaab MR: Infrared-based neuronavigation and cortical motor stimulation in the management of central-region tumors Stereotact Funct Neurosurg 68:112–116, 1997

    PubMed  CAS  Google Scholar 

  184. Walsh AR, Schmidt RH, Marsh HT, Cortical mapping and resection under local anesthetic as an aid to surgery of low and intermediate grade gliomasBr J Neurosurg4: 485–491, 1990

    PubMed  CAS  Google Scholar 

  185. Whittle IR, Borthwick S, Haq N, Brain dysfunction following “awake” craniotomy, brain mapping and resection of gliomaBr J Neurosurg17: 130–137, 2003

    Article  PubMed  CAS  Google Scholar 

  186. Whittle IR, Midgley S, Georges H, Pringle AM, Taylor R: Patient perceptions of “awake” brain tumour surgery Acta Neurochir (Wien). 147: 275–127, 2005

    Article  CAS  Google Scholar 

  187. Duffau H, Peroperative functional mapping using direct electrical stimulations. Methodological considerationsNeurochirurgie50: 474–483, 2004

    Article  PubMed  CAS  Google Scholar 

  188. Ojemann G, Ojemann G, Lettich E, Berger M, Cortical language localization in left, dominant hemisphere. An electrical stimulation mapping investigation in 117 patientsJ Neurosurg 71: 316–326, 1989

    PubMed  CAS  Google Scholar 

  189. Duffau H, Capelle L, Denvil D, Gatignol P, Sichez N, Lopes M, Sichez JP, Van Effenterre R: The role of dominant premotor cortex in language: a study using intraoperative functional mapping in awake patients Neuroimage 20: 1903–1914, 2003

    Article  PubMed  Google Scholar 

  190. Gatignol P, Capelle L, Le Bihan R, Duffau H, Double dissociation between picture naming and comprehension: an electrostimulation studyNeuroreport15: 191–195, 2004

    Article  PubMed  Google Scholar 

  191. Freund H, Supplementary sensorimotor area. Historical overviewAdv Neurol70: 17–27, 1996

    PubMed  CAS  Google Scholar 

  192. Lim SH, Dinner DS, Pillay PK, Luders H, Morris HH, Klem G, Wyllie E, Awad IA: Functional anatomy of the supplementary sensorimotor area: results of extraoperative electrical stimulation Electroencephalogr Clin Neurophysiol 91: 179–193, 1994

    Article  PubMed  CAS  Google Scholar 

  193. Picard N, Strick PL, Imaging the premotor areasCurr Opin Neurobiol11: 663–672, 2001

    Article  PubMed  CAS  Google Scholar 

  194. Bannur U, Rajshekhar V, Postoperative supplementary motor area syndrome: clinical features and outcomeBr J Neurosurg14: 204–210, 2000

    Article  PubMed  CAS  Google Scholar 

  195. Bleasel A, Comair Y, Lüders H, 1996 Surgical ablation of the mesial frontal lobe in humans. In Lüders H, (ed). Supplementary Sensorimotor AreaLippincott-Raven Philadelphia, 217–235

    Google Scholar 

  196. Fukaya C, Katayama Y, Kobayashi K, Kasai M, Oshima H, Yamamoto T: Impairment of motor function after frontal lobe resection with preservation of the primary motor cortex Acta Neurochir Suppl 87: 71–74, 2003

    PubMed  CAS  Google Scholar 

  197. Laplane D, Talairach J, Meininger V, Bancaud J, Orgogozo JM: Clinical consequences of corticectomies involving the Supplementary Motor Area in man J Neurol Sci 34: 301–314, 1977

    Article  PubMed  CAS  Google Scholar 

  198. Rostomily RC, Berger MS, Ojemann GA, Lettich E, Postoperative deficits and functional recovery following removal of tumors involving the dominant hemisphere supplementary motor areaJ Neurosurg75: 62–68, 1991

    PubMed  CAS  Google Scholar 

  199. Russell SM, Kelly PJ Incidence and clinical evolution of postoperative deficits after volumetric stereotactic resection of glial neoplasm involving the supplementary motor area Neurosurgery52: 506–516, 2003

    Article  PubMed  Google Scholar 

  200. Yamane F, Muragaki Y, Maruyama T, Okada Y, Iseki H, Ikeda A, Homma I, Hori T: Preoperative mapping for patients with supplementary motor area epilepsy: multimodality brain mapping Psychiatry Clin Neurosci 58: S16–21, 2004

    Article  PubMed  Google Scholar 

  201. Zentner J, Hufnagel A, Pechstein U, Wolf HK, Schramm J: Functional results after resective procedures involving the supplementary motor area J Neurosurg 85: 542–549, 1996

    PubMed  CAS  Google Scholar 

  202. Duffau H, Lopes M, Denvil D, Capelle L, Delayed onset of the supplementary motor area syndrome after surgical resection of the mesial frontal lobe: a time course study using intraoperative mapping in an awake patientStereotact Funct Neurosurg76: 74–82, 2001

    Article  PubMed  CAS  Google Scholar 

  203. Krainik A, Lehericy S, Duffau H, Capelle L, Chainay H, Cornu P, Cohen L, Boch AL, Mangin JF, Le Bihan D, Marsault C: Postoperative speech disorder after medial frontal surgery: role of the supplementary motor area Neurology 60: 587–594, 2003

    PubMed  CAS  Google Scholar 

  204. Fontaine D, Capelle L, Duffau H, Somatotopy of the supplementary motor area: evidence from correlation of the extent of surgical resection with the clinical patterns of deficit Neurosurgery50: 297–303, 2002

    Article  PubMed  Google Scholar 

  205. Ackermann H, Riecker A, The contribution of the insula to motor aspects of speech production: a review and a hypothesisBrain Lang89: 320–328, 2004

    Article  PubMed  Google Scholar 

  206. Wise RJ, Greene J, Buchel C, Scott SK, Brain regions involved in articulationLancet 353: 1057–1061, 1999

    Article  PubMed  CAS  Google Scholar 

  207. Duffau H, Capelle L, Lopes M, Faillot T, Sichez JP, Fohanno D: The insular lobe: physiopathological and surgical considerations Neurosurgery 47: 801–810, 2000

    Article  PubMed  CAS  Google Scholar 

  208. Duffau H, Fontaine D, Successful resection of a left insular cavernous angioma using neuronavigation and intraoperative language mappingActa Neurochir (Wien)147: 205–208, 2005

    Article  CAS  Google Scholar 

  209. Dronkers NF, A new brain region for coordinating speech articulationNature384: 159–161, 1996

    Article  PubMed  CAS  Google Scholar 

  210. Duffau H, Taillandier L, Gatignol P, Capelle L: The insular lobe and brain plasticity: lessons from tumor surgery. Clin Neurol Neurosurg, in press

  211. Duffau H, Karachi C, Gatignol P, Capelle L, Transient Foix–Chavany–Marie syndrome following surgerical resection of a right insulo-opercular low-grade glioma: case report Neurosurgery53: 426–431, 2003

    Article  PubMed  Google Scholar 

  212. Freund HJ, Functional organization of the human supplementary motor area and dorsolateral premotor cortexAdv Neurol70: 263–269, 1996

    PubMed  CAS  Google Scholar 

  213. Grafton ST, Fadiga L, Arbib MA, Rizzolatti G, Premotor activation during observation during observation and naming of familiar toolsNeuroimage 6: 231–236, 1997

    Article  PubMed  CAS  Google Scholar 

  214. Martin A, Wiggs CL, Ungerleider LG, Haxby JV, Neural correlates of category-specific knowledgeNature379: 649–652, 1996

    Article  PubMed  CAS  Google Scholar 

  215. Cohen L, Benoit N, Van Eeckhout P, Ducarne B, Brunet P: Pure progressive aphemia J Neurol Neurosurg Psychiatry 56: 923–924, 1993

    Article  PubMed  CAS  Google Scholar 

  216. Fox RJ, Kasner SE, Chatterjee A, Chalela JA, Aphemia: an isolated disorder of articulationClin Neurol Neurosurg103: 123–126, 2001

    Article  PubMed  CAS  Google Scholar 

  217. Dehaene S, Molko N, Cohen L, Wilson AJ, Arithmetic and the brainCurr Opin Neurobiol 14: 218–224, 2004

    Article  PubMed  CAS  Google Scholar 

  218. Duffau H, Denvil D, Lopes M, Gasparini F, Cohen L, Capelle L, Van Effenterre R: Intraoperative mapping of the cortical areas involved in multiplication and subtraction: an electrostimulation study in a patient with a left parietal glioma J Neurol Neurosurg Psychiatry 73: 733–738, 2002

    Article  PubMed  CAS  Google Scholar 

  219. Gasparini FM, Cohen L, Lopes M, Denvil D, Capelle L, Duffau H, Van Effenterre R: A clinical study of the number processing system: decimal size effects on reading numbers in patients with left parieto-occipital gliomas Rev Neurol (Paris) 161: 427–435, 2005

    CAS  Google Scholar 

  220. Boatman D, Gordon B, Hart J, Selnes O, Miglioretti D, Lenz F: Transcortical sensory aphasia: revisited and revised Brain 123: 1634–1642, 2000

    Article  PubMed  Google Scholar 

  221. Duffau H, Gatignol P, Mandonnet E, Peruzzi P, Tzourio-Mazoyer N, Capelle L: New insights into the anatomo-functional connectivity of the semantic system: a study using cortico-subcortical electrostimulations Brain 128: 797–810, 2005

    Article  PubMed  Google Scholar 

  222. Vigneau M, Beaucousin V, Hervé PY, Duffau H, Crivello F, Houdé O, Mazoyer B, Tzourio-Mazoyer N: Meta-analysing the left hemisphere langaueg areas: phonology, semantics and sentence processing. Neuroimage, in press

  223. Blanke O, Seeck M, Direction of saccadic and smooth eye movements induced by electrical stimulation of the human frontal eye field: effect of orbital positionExp Brain Res150: 174–183, 2003

    PubMed  Google Scholar 

  224. Lobel E, Kahane P, Leonards U, Grosbras M, Lehericy S, Le Bihan D, Berthoz A: Localization of human frontal eye fields: anatomical and functional findings of functional magnetic resonance imaging and intracerebral electrical stimulation J Neurosurg 95: 804–815, 2001

    PubMed  CAS  Google Scholar 

  225. Milea D, Lobel E, Lehericy S, Duffau H, Rivaud-Pechoux S, Berthoz A, Pierrot-Deseilligny C: Intraoperative frontal eye field stimulation elicits ocular deviation and saccade suppression Neuroreport 13: 1359–1364, 2002

    Article  PubMed  Google Scholar 

  226. Milea D, Lehericy S, Rivaud-Pechoux S, Duffau H, Lobel E, Capelle L, Marsault C, Berthoz A, Pierrot-Deseilligny C: Antisaccade deficit after anterior cingulate cortex resection Neuroreport 14: 283–287, 2003

    Article  PubMed  CAS  Google Scholar 

  227. Thiebaut de Schotten M, Urbanski M, Duffau H, Volle E, Levy R, Dubois B, Bartolomeo P: Direct evidence for a parietal-frontal pathway subserving spatial awareness in humans Science 309: 2226–2228, 2005

    Article  PubMed  CAS  Google Scholar 

  228. Roux FE, Boetto S, Sacko O, Chollet F, Tremoulet M: Writing, calculating, and finger recognition in the region of the angular gyrus: a cortical stimulation study of Gerstmann syndrome J Neurosurg 99: 716–727, 2003

    PubMed  Google Scholar 

  229. Roux FE, Lubrano V, Lauwers-Cances V, Tremoulet M, Mascott CR, Demonet JF: Intra-operative mapping of cortical areas involved in reading in mono- and bilingual patients Brain 127: 1796–1810, 2004

    Article  PubMed  Google Scholar 

  230. Lucas TH, McKhann GM, Ojemann GA, Functional separation of languages in the bilingual brain: a comparison of electrical stimulation language mapping in 25 bilingual patients and 117 monolingual control patientsJ Neurosurg101: 449–457, 2004

    PubMed  Google Scholar 

  231. Roux FE, Tremoulet M, Organization of language areas in bilingual patients: a cortical stimulation studyJ Neurosurg97: 857–864, 2002

    PubMed  Google Scholar 

  232. Duffau H, Capelle L, Incontinence after brain glioma surgery: new insights into the cortical control of micturition and continence. Case reportJ Neurosurg102: 148–151, 2005

    PubMed  Google Scholar 

  233. Couldwell WT, Yong VW, Glioma invasionJ Neurosurg95: 379–380, 2001

    PubMed  CAS  Google Scholar 

  234. Coenen VA, Krings T, Mayfrank L, Polin RS, Reinges MH, Thron A, Gilsbach JM: Three-dimensional visualization of the pyramidal tract in a neuronavigation system during brain tumor surgery: first experiences and technical note Neurosurgery 49: 86–92, 2001

    Article  PubMed  CAS  Google Scholar 

  235. Lang FF, Olansen NE, DeMonte F, Gokaslan ZL, Holland EC, Kalhorn C, Sawaya R: Surgical resection of intrinsic insular tumors: complication avoidance J Neurosurg 95: 638–650, 2001

    PubMed  CAS  Google Scholar 

  236. Le Bihan D, Looking into the functional architecture of the brain with diffusion MRINat Rev Neurosci4: 469–480, 2003

    Article  PubMed  CAS  Google Scholar 

  237. Catani M, Howard RJ, Pajevic S, Jones DK, Virtual in vivo interactive dissection of white matter fasciculi in the human brainNeuroimage17: 77–94, 2002

    Article  PubMed  Google Scholar 

  238. Sinha S, Bastin ME, Whittle IR, Wardlaw JM, Diffusion tensor MR imaging of high-grade cerebral gliomasAm J Neuroradiol23: 520–527, 2002

    PubMed  Google Scholar 

  239. Gossl C, Fahrmeir L, Putz B, Auer LM, Auer DP: Fiber tracking from DTI using linear state space models: detectability of the pyramidal tract Neuroimage 16: 378–388, 2002

    Article  PubMed  CAS  Google Scholar 

  240. Witwer BP, Moftakhar R, Hasan KM, Deshmukh P, Haughton V, Field A, Arfanakis K, Noyes J, Moritz CH, Meyerand ME, Rowley HA, Alexander AL, Badie B: Diffusion-tensor imaging of white matter tracts in patients with cerebral neoplasm J Neurosurg 97: 568–575, 2002

    PubMed  Google Scholar 

  241. Hendler T, Pianka P, Sigal M, Kafri M, Ben-Bashat D, Constantini S, Graif M, Fried I, Assaf Y: Diffusion-tensor imaging of white matter tracts in patients with cerebral neoplasm J Neurosurg 99: 1018–1027, 2003

    PubMed  Google Scholar 

  242. Berman JI, Berger MS, Mukherjee P, Henry RG, Diffusion-tensor imaging-guided tracking of fibers of the pyramidal tract combined with intraoperative cortical stimulation mapping in patients with gliomasJ Neurosurg101: 66–72, 2004

    PubMed  Google Scholar 

  243. Holodny AI, Ollenschleger M, Diffusion imaging in brain tumorsNeuroimaging Clin N Am 12: 107–124, 2002

    Article  PubMed  Google Scholar 

  244. Lin CP, Tseng WY, Cheng HC, Chen JH Validation of diffusion tensor magnetic resonance axonal fiber imaging with registered manganese-enhanced optic tractsNeuroimage14: 1035–1047, 2001

    Article  PubMed  CAS  Google Scholar 

  245. Coenen VA, Krings T, Axer H, Weidemann J, Kranzlein H, Hans FJ, Thron A, Gilsbach JM, Rohde V: Intraoperative three-dimensional visualization of the pyramidal tract in a neuronavigation system (PTV) reliably predicts true position of principal motor pathways Surg Neurol 60: 381–390, 2003

    Article  PubMed  Google Scholar 

  246. Holodny AI, Schwartz TH, Ollenschleger M, Liu WC, Schulder M: Tumor involvement of the corticospinal tract: diffusion magnetic resonance tractography with intraoperative correlation J Neurosurg 95: 1082, 2001

    PubMed  CAS  Google Scholar 

  247. Duffau H, Capelle L, Denvil D, Sichez N, Gatignol P, Taillandier L, Lopes M, Mitchell MC, Roche S, Muller JC, Bitar A, Sichez JP, van Effenterre R: Usefulness of intraoperative electrical subcortical mapping during surgery for low-grade gliomas located within eloquent brain regions: functional results in a consecutive series of 103 patients J Neurosurg 98: 764–778, 2003

    PubMed  Google Scholar 

  248. Berger MS, Ojemann GA, Intraoperative brain mapping techniques in neuro-oncologyStereotact Funct Neurosurg58: 153–161, 1992

    PubMed  CAS  Google Scholar 

  249. Berger MS, Lesions in functional (“eloquent”) cortex and subcortical white matterClin Neurosurg41: 444–463, 1994

    PubMed  CAS  Google Scholar 

  250. Berger MS, Functional mapping-guided resection of low-grade gliomasClin Neurosurg42: 437–452, 1995

    PubMed  CAS  Google Scholar 

  251. Eisner W, Burtscher J, Bale R, Sweeney R, Koppelstatter F, Golaszewski S, Kolbitsch C, Twerdy K: Use of neuronavigation and electrophysiology in surgery of subcortically located lesions in the sensorimotor strip J Neurol Neurosurg Psychiatry 2002; 72: 378–381, 2002

    CAS  Google Scholar 

  252. Haglund MM, Berger M, Functional mapping of motor, sensory and language pathways during low-grade glioma removalTech Neurosurg2: 141–149, 1996

    Google Scholar 

  253. Keles GE, Lundin DA, Lamborn KR, Chang EF, Ojemann G, Berger MS: Intraoperative subcortical stimulation mapping for hemispherical perirolandic gliomas located within or adjacent to the descending motor pathways: evaluation of morbidity and assessment of functional outcome in 294 patients J Neurosurg 100: 369–375, 2004

    Article  PubMed  Google Scholar 

  254. Skirboll SS, Ojemann GA, Berger MS, Lettich E, Winn HR: Functional cortex and subcortical white matter located within gliomas Neurosurgery 38: 678–684, 1996

    Article  PubMed  CAS  Google Scholar 

  255. Vinas FC, Zamorano L, Mueller RA, Jiang Z, Chugani H, Fuerst D, Muzik O, Mangner TJ, Diaz FG: [15O]-water PET and intraoperative brain mapping: a comparison in the localization of eloquent cortex Neurol Res 1997; 19:601–608

    PubMed  CAS  Google Scholar 

  256. Yingling CD, Ojemann S, Dodson B, Harrington MJ, Berger MS: Identification of motor pathways during tumor surgery facilitated by multichannel electromyographic recording J Neurosurg 91: 922–927, 1999

    PubMed  CAS  Google Scholar 

  257. Duffau H, Intraoperative cortico-subcortical stimulations in surgery of low-grade gliomas Expert Rev Neurother5: 473–485, 2005

    Article  PubMed  Google Scholar 

  258. Duffau H, Velut S, Mitchell MC, Gatignol P, Capelle L: Intra-operative mapping of the subcortical visual pathways using direct electrical stimulations Acta Neurochir (Wien) 146: 265–269, 2004

    Article  CAS  Google Scholar 

  259. Duffau H, Capelle L, Sichez N, Denvil D, Lopes M, Sichez JP, Bitar A, Fohanno D: Intraoperative mapping of the subcortical language pathways using direct stimulations. An anatomo-functional study Brain 125: 199–214, 2002

    Article  PubMed  Google Scholar 

  260. Duffau H, Gatignol P, Denvil D, Lopes M, Capelle L: The articulatory loop: study of the subcortical connectivity by electrostimulation Neuroreport 14: 2005–2008, 2003

    Article  PubMed  Google Scholar 

  261. Catani M, Jones DK, Ffytche DH, Perisylvian language networks of the human brainAnn Neurol57: 8–16, 2005

    Article  PubMed  Google Scholar 

  262. Gil Robles S, Gatignol P, Capelle L, Mitchell MC, Duffau H: The role of dominant striatum in language: a study using intraoperative electrical stimulations J Neurol Neurosurg Psychiatry 76:940–946, 2005

    Article  PubMed  CAS  Google Scholar 

  263. Geschwind N, The organization of language and the brainScience170: 940, 1970

    PubMed  CAS  Google Scholar 

  264. Mechelli A, Penny WD, Price CJ, Effective connectivity and intersubject variability: using a multisubject network to test differences and commonalitiesNeuroImage17: 1459, 2002

    Article  PubMed  Google Scholar 

  265. McClelland J, Rogers TT, The parallel distributed processing approach to semantic cognition Nat Rev Neurosci4: 310, 2003

    Article  PubMed  CAS  Google Scholar 

  266. Mesulam MM, Large-scale neurocognitive networks and distributed processing for attention, language, and memoryAnn Neurol28: 597, 1990

    Article  PubMed  CAS  Google Scholar 

  267. Bartels A, Zeki S, The chronoarchitecture of the cerebral cortexPhilos Trans R Soc Lond B Biol Sci360: 733, 2005

    Article  PubMed  Google Scholar 

  268. Horwitz B, Braun AR, Brain network interactions in auditory, visual and linguistic processingBrain Lang89: 377, 2004

    Article  PubMed  Google Scholar 

  269. Bartolomei F, Bosma I, Klein M, Baayen JC, Reijneveld JC, Postma TJ, Heimans JJ, van Dijk BW, de Munck JC, de Jongh A, Cover KS, Stam CJ: How do brain tumors alter functional connectivity? A magnetoencephalography study Ann Neurol 59:128–138, 2006

    Article  PubMed  Google Scholar 

  270. Soltmann O, Experimentalle studien über die functionen des grosshirns der neugeborenen Jahrb Kinderheilkd 9:106–148, 1876

    Google Scholar 

  271. Barlow T, On a case of double hemiplegia with cerebral symmetrical lesionsBr Med J 2:103–104, 1877

    Article  Google Scholar 

  272. von Monakow C, Die lokalisation im groshirn un der abbau der funktion durch kortikale herdeWiesbaden, Germany: Bergman JF 26–34, 1914

    Google Scholar 

  273. Kennard MA, Age and other factors in motor recovery from precentral lesions in monkeysAm J Physiol115: 138–146, 1936

    Google Scholar 

  274. Bethe A, Fischer E, 1931 Die Anpassungsfähigkeit (Plastizität) des Nervensystems. In Bethe A, von Bergmann G, Emden G, Ellinger A, Hrsg, (eds). Handbuch der Normalen und Pathologischen PhysiologieSpringer, Bd 15/2Berlin, 1045–1130

    Google Scholar 

  275. Duffau H: Brain plasticity: from pathophysiological mechanisms to therapeutic applications. J Clin Neurosci, in press

  276. Byrne JH Synapses. Plastic plasticityNature 389: 791–792, 1997

    Article  PubMed  CAS  Google Scholar 

  277. Jacobs KM, Donoghue JP Reshaping the cortical motor map by unmasking latent intracortical connectionsScience251: 944–947, 1991

    PubMed  CAS  Google Scholar 

  278. Ivanco TL, Greenough WT, Physiological consequences of morphologically detectable synaptic plasticity: potential uses for examining recovery following damageNeuropharmacology 39: 765–776, 2000

    Article  PubMed  CAS  Google Scholar 

  279. Gross CG, Neurogenesis in the adult brain: death of a dogmaNat Rev Neurosci1: 67–73, 2000

    Article  PubMed  CAS  Google Scholar 

  280. Nguyen DK, Botez MI, Diaschisis and neurobehaviorCan J Neurol Sci25:5–12, 1998

    PubMed  CAS  Google Scholar 

  281. Duffau H, Sichez JP, Lehéricy S, Intraoperative unmasking of brain redundant motor sites during resection of a precentral angioma: evidence using direct cortical stimulationAnn Neurol 47: 132–135, 2000

    Article  PubMed  CAS  Google Scholar 

  282. Bavelier D, Neville HJ Cross-modal plasticity: where and how?Nat Rev Neurosci 3: 443–452, 2002

    PubMed  CAS  Google Scholar 

  283. Draganski B, Gaser C, Busch V, Schuierer G, Bogdahn U, May A: Neuroplasticity: changes in grey matter induced by training Nature 427: 311–312, 2004

    Article  PubMed  CAS  Google Scholar 

  284. Jonhson MH Development of human brain functionsBiol Psychiatry54: 1312–1316, 2003

    Article  PubMed  Google Scholar 

  285. Karni A, Meyer G, Rey-Hipolito C, Jezzard P, Adams MM, Turner R, Ungerleider LG: The acquisition of skilled motor performance: fast and slow experience-driven changes in primary motor cortex Proc Natl Acad Sci U S A 95: 861–868, 1998

    Article  PubMed  CAS  Google Scholar 

  286. Chen R, Cohen LG, Hallett M, Nervous system reorganization following injury Neuroscience111: 761–773, 2002

    Article  PubMed  CAS  Google Scholar 

  287. Kolb B, Overview of cortical plasticity and recovery from brain injuryPhys Med Rehabil Clin N Am14: S7–S25, 2003

    PubMed  Google Scholar 

  288. Butefisch CM, Plasticity in the human cerebral cortex: lessons from the normal brain and from strokeNeuroscientist10: 163–173, 2004

    Article  PubMed  Google Scholar 

  289. Rijntjes M, Weiller C, Recovery of motor and language abilities after stroke: the contribution of functional imagingProg Neurobiol66: 109–122, 2002

    Article  PubMed  Google Scholar 

  290. Hallett M, Plasticity of the human motor cortex and recovery from strokeBrain Res Brain Res Rev36: 169–174, 2001

    Article  PubMed  CAS  Google Scholar 

  291. Nudo RJ, Functional and structural plasticity in motor cortex: implications for stroke recoveryPhys Med Rehabil Clin N Am14: S57–S76, 2003

    PubMed  Google Scholar 

  292. Rossini PM, Calautti C, Pauri F, Baron JC, Post-stroke plastic reorganisation in the adult brainLancet Neurol2: 493–502, 2003

    Article  PubMed  Google Scholar 

  293. Thirumala P, Hier DB, Patel P, Motor recovery after stroke: lessons from functional brain imagingNeurol Res24: 453–458, 2002

    Article  PubMed  Google Scholar 

  294. Fandino J, Kollias SS, Wieser HG, Valavanis A, Yonekawa Y: Intraoperative validation of functional magnetic resonance imaging and cortical reorganization patterns in patients with brain tumors involving the primary motor cortex J Neurosurg 91: 238–250, 1999

    PubMed  CAS  Google Scholar 

  295. Carpentier AC, Constable RT, Schlosser MJ, de Lotbiniere A, Piepmeier JM, Spencer DD, Awad IA: Patterns of functional magnetic resonance imaging activation in association with structural lesions in the rolandic region: a classification system J Neurosurg 94: 946–954, 2001

    PubMed  CAS  Google Scholar 

  296. Schiffbauer H, Ferrari P, Rowley HA, Berger MS, Roberts TP: Functional activity within brain tumors: a magnetic source imaging study Neurosurgery 49: 1313–1320, 2001

    Article  PubMed  CAS  Google Scholar 

  297. Atlas SW, Howard RS 2nd, Maldjian J, Alsop D, Detre JA, Listerud J, Dȁ9Esposito M, Judy KD, Zager E, Stecker M: Functional magnetic resonance imaging of regional brain activity in patients with intracerebral gliomas: findings and implications for clinical management Neurosurgery 38: 329–338, 1996

    Article  PubMed  CAS  Google Scholar 

  298. Wunderlich G, Knorr U, Herzog H, Kiwit JC, Freund HJ, Seitz RJ: Precentral glioma location determines the displacement of cortical hand representation Neurosurgery 42: 18–27, 1998

    Article  PubMed  CAS  Google Scholar 

  299. Heiss WD, Thiel A, Kessler J, Herholz K, Disturbance and recovery of language function: correlates in PET activation studiesNeuroImage20: S42–49, 2003

    Article  PubMed  Google Scholar 

  300. Seitz RJ, Huang Y, Knorr U, Tellmann L, Herzog H, Freund HJ. Large-scale plasticity of the human motor cortex Neuroreport 6: 742–744, 1995

    PubMed  CAS  Google Scholar 

  301. Thiel A, Herholz K, Koyuncu A, Ghaemi M, Kracht LW, Habedank B, Heiss WD: Plasticity of language networks in patients with brain tumors: a positron emission tomography activation study Ann Neurol 50: 620–629, 2001

    Article  PubMed  CAS  Google Scholar 

  302. Ulmer JL, Hacein-Bey L, Mathews VP, Mueller WM, DeYoe EA, Prost RW, Meyer GA, Krouwer HG, Schmainda KM: Lesion-induced pseudo-dominance at functional magnetic resonance imaging: implications for preoperative assessments Neurosurgery 55: 569–579, 2004

    Article  PubMed  Google Scholar 

  303. Baciu M, Le Bas JF, Segebarth C, Benabid AL, Presurgical fMRI evaluation of cerebral reorganization and motor deficit in patients with tumors and vascular malformationsEur J Radiol 46: 139–146, 2003

    Article  PubMed  CAS  Google Scholar 

  304. Caramia MD, Telera S, Palmieri MG, Wilson-Jones M, Scalise A, Iani C, Giuffre R, Bernardi G: Ipsilateral motor activation in patients with cerebral gliomas Neurology 51: 196–202, 1998

    PubMed  CAS  Google Scholar 

  305. Holodny AI, Schulder M, Ybasco A, Liu WC, Translocation of Brocaȁ9s area to the contralateral hemisphere as the result of the growth of a left inferior frontal gliomaJ Comput Assist Tomogr26: 941–943, 2002

    Article  PubMed  Google Scholar 

  306. Roux FE, Boulanouar K, Ibarrola D, Tremoulet M, Chollet F, Berry I: Functional MRI and intraoperative brain mapping to evaluate brain plasticity in patients with brain tumours and hemiparesis J Neurol Neurosurg Psychiatry 69: 453–463, 2000

    Article  PubMed  CAS  Google Scholar 

  307. Taniguchi M, Kato A, Ninomiya H, Hirata M, Cheyne D, Robinson SE, Maruno M, Saitoh Y, Kishima H, Yoshimine T: Cerebral motor control in patients with gliomas around the central sulcus studied with spatially filtered magnetoencephalography J Neurol Neurosurg Psychiatry 75: 466–471, 2004

    Article  PubMed  CAS  Google Scholar 

  308. Branco DM, Coelho TM, Branco BM, Schmidt L, Calcagnotto ME, Portuguez M, Neto EP, Paglioli E, Palmini A, Lima JV, Da Costa JC: Functional variability of the human cortical motor map: electrical stimulation findings in perirolandic epilepsy surgery J Clin Neurophysiol 20: 17–25, 2003

    Article  PubMed  Google Scholar 

  309. Duffau H, Acute functional reorganisation of the human motor cortex during resection of central lesions: a study using intraoperative brain mappingJ Neurol Neurosurg Psychiatry70: 506–513, 2001

    Article  PubMed  CAS  Google Scholar 

  310. Duffau H, Capelle L, Functional recuperation following lesions of the primary somatosensory fields. Study of compensatory mechanismsNeurochirurgie47: 557–563, 2001

    PubMed  CAS  Google Scholar 

  311. Duffau H, Recovery from complete hemiplegia following resection of a retrocentral metastasis: the prognostic value of intraoperative cortical stimulationJ Neurosurg95: 1050–1052, 2001

    Article  PubMed  CAS  Google Scholar 

  312. Kamada K, Sawamura Y, Takeuchi F, Houkin K, Kawaguchi H, Iwasaki Y, Kuriki S: Gradual recovery from dyslexia and related serial magnetoencephalographic changes in the lexicosemantic centers after resection of a mesial temporal astrocytoma Case report J Neurosurg 100: 1101–1106, 2004

    PubMed  Google Scholar 

  313. Krainik A, Duffau H, Capelle L, Cornu P, Boch AL, Mangin JF, Le Bihan D, Marsault C, Chiras J, Lehericy S: Role of the healthy hemisphere in recovery after resection of the supplementary motor area Neurology 62: 1323–1332, 2004

    PubMed  CAS  Google Scholar 

  314. Duffau H, Bauchet L, Lehericy S, Capelle L, Functional compensation of the left dominant insula for languageNeuroreport12: 2159–2163, 2001

    Article  PubMed  CAS  Google Scholar 

  315. Duffau H, Capelle L, Lopes M, Bitar A, Sichez JP, van Effenterre R: Medically intractable epilepsy from insular low-grade gliomas: improvement after an extended lesionectomy Acta Neurochir (Wien) 144: 563–572, 2002

    Article  CAS  Google Scholar 

  316. Duffau H, Kujas M, Taillandier L: Epileptic nocturnal wandering in a right temporo-insular low-grade glioma: relief following surgical resection. Case report. J Neurosurg, in press

  317. Isnard J, Guenot M, Ostrowsky K, Sindou M, Mauguiere F: The role of the insular cortex in temporal lobe epilepsy Ann Neurol 48: 614–623, 2000

    Article  PubMed  CAS  Google Scholar 

  318. LeRoux PD, Berger MS, Haglund MM, Pilcher WH, Ojemann GA: Resection of intrinsic tumors from nondominant face motor cortex using stimulation mapping: report of two cases Surg Neurol 36: 44–48, 1991

    Article  PubMed  CAS  Google Scholar 

  319. Duffau H, Denvil D, Capelle L, Absence of movement disorders after surgical resection of glioma invading the right striatumJ Neurosurg97(3) 63–369, 2002

    PubMed  Google Scholar 

  320. Barker R, Model for basal ganglia disordersTrends Neurosci13: 93, 1990

    Article  PubMed  CAS  Google Scholar 

  321. Lang AE, Hemiballism-hemichoreaArch Neurol47: 619, 1990

    PubMed  CAS  Google Scholar 

  322. Zagnoli F, Rouhart F, Perotte P, Bellard S, Goas JY: Hémichorée et infarctus striatal Rev Neurol (Paris) 152: 615–622, 1996

    CAS  Google Scholar 

  323. Duffau H, Denvil D, Capelle L, Long term reshaping of language, sensory, and motor maps after glioma resection: a new parameter to integrate in the surgical strategJ Neurol Neurosurg Psychiatry72: 511–516, 2002

    PubMed  CAS  Google Scholar 

  324. Horwitz B, The elusive concept of brain connectivityNeuroimage2003; 19:466–470

    Article  PubMed  Google Scholar 

  325. Krainik A, Marrelec G, Duffau H, Capelle L, Cornu P, Boch Al, Mangin Jf, Le Bihan D, Marsault C, Chiras J, Benali H, Lehericy S: Anatomical and functional premotor correlations in supplementary motor area lesion Eur Radiol 14: 536, 2004

    Google Scholar 

  326. Penny WD, Stephan KE, Mechelli A, Friston KJ, Modelling functional integration: a comparison of structural equation and dynamic causal modelsNeuroimage23: S264–S274, 2004

    Article  PubMed  Google Scholar 

  327. Tzourio-Mazoyer N, Josse G, Crivello F, Mazoyer B, Interindividual variability in the hemispheric organization for speechNeuroImage2004; 21: 422–435

    Article  PubMed  CAS  Google Scholar 

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  1. Department of Neurosurgery, UMR-S678 Inserm, Hôpital Salpêtrière, Paris, France

    Hugues Duffau

  2. Department of Neurosurgery, UMR-S678 Inserm, Hôpital Salpêtrière, 47-83 Bd de l’hôpital, 75013, Paris, France

    Hugues Duffau

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Duffau, H. New concepts in surgery of WHO grade II gliomas: functional brain mapping, connectionism and plasticity – a review. J Neurooncol 79, 77–115 (2006). https://doi.org/10.1007/s11060-005-9109-6

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