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Vascular Neural Network: the Importance of Vein Drainage in Stroke

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Abstract

This perspective commentary summarized the stroke pathophysiology evolution, especially the focus in the past on neuroprotection and neurovascular protection and highlighted the newer term for stroke pathophysiology: vascular neural network. Emphasis is on the role of venules and veins after an acute stroke and as potential treatment targets. Vein drainage may contribute to the acute phase of brain edema and the outcomes of stroke patients.

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Conflict of Interest

The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Department of Neurology, The Fifth People’s Hospital of Chongqing, Chongqing, China, 400062

    Qian Li

  2. Department of Anesthesiology, Loma Linda University Medical Center, Loma Linda, CA, USA

    Nikan Khatibi & John H. Zhang

  3. Department of Neurosurgery, Department of Physiology, Loma Linda University School of Medicine, Loma Linda, CA, 92350, USA

    John H. Zhang

Authors
  1. Qian Li
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  2. Nikan Khatibi
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  3. John H. Zhang
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Correspondence to John H. Zhang.

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Li, Q., Khatibi, N. & Zhang, J.H. Vascular Neural Network: the Importance of Vein Drainage in Stroke. Transl. Stroke Res. 5, 163–166 (2014). https://doi.org/10.1007/s12975-014-0335-0

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  • DOI: https://doi.org/10.1007/s12975-014-0335-0

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