Intracellular diffusion of water☆
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Cited by (105)
Thermal effects connected to crystallization dynamics: A lattice Boltzmann study
2024, International Journal of Multiphase FlowConstant gradient FEXSY: A time-efficient method for measuring exchange
2020, Journal of Magnetic ResonanceCitation Excerpt :Nonetheless, transmembranal water exchange is affected by a myriad of processes that take place in living cells, and could thus potentially provide indication on tissue state. Indeed, in the last few decades, MR measurement of exchange rates were shown to be sensitive to a diverse set of cellular conditions and pathologies [18–22]. Furthermore, recent studies suggest that diagnosis of central nervous system (CNS) pathologies based on exchange measurements is possible [23].
Physical and numerical phantoms for the validation of brain microstructural MRI: A cookbook
2018, NeuroImageCitation Excerpt :Yeast is a well-studied eukaryotic model organism that in suspension has been used as a two-component system featuring isotropic diffusion of both the intracellular and extracellular water with exchange in between. Yeast cells are spherical with a diameter of about 3–7 μm (Silva et al., 2002; Tanner, 1983), intracellular diffusivity of ∼0.65 μm2/ms at room temperature (Åslund and Topgaard, 2009), extracellular diffusivity depending on the packing density of the cell suspension (e.g., 1.2 μm2/ms at room temperature for an intracellular fraction of 0.41), and exchange times measured to be in the range of 250 ms (Table VI in (Tanner, 1983)), and 280 ms in (Åslund et al., 2009). Since the first characterization by Tanner (Tanner, 1983; Tanner and Stejskal, 1968), yeast cell suspensions have been shown very useful as a simple well-characterized phantom to validate methods for assessing exchange, intracellular diffusion, and compartment shapes (Åslund et al., 2009; Åslund and Topgaard, 2009; Cory and Garroway, 1990; Eriksson et al., 2013; Lasič et al., 2011, 2014; Shemesh et al., 2011, 2012; Silva et al., 2002).
Exploring diffusion across permeable barriers at high gradients. I. Narrow pulse approximation
2014, Journal of Magnetic ResonancePerfusion and diffusion sensitive <sup>13</sup>C stimulated-echo MRSI for metabolic imaging of cancer
2013, Magnetic Resonance ImagingCitation Excerpt :Because the encoding strength (b-value) is proportional to γ2, this is especially important in 13C, which has a gyromagnetic ratio, γ, that is about 4-times smaller than that of 1H. Compartmentalization of metabolites has been performed on cell cultures with diffusion-weighted 1H MRS [30–38]. These studies demonstrated diffusion-weighting can be used for separation of intracellular metabolites.
Isotropic diffusion weighting in PGSE NMR by magic-angle spinning of the q-vector
2013, Journal of Magnetic Resonance
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The experimental portions of this work have been reported in Technical Report No. NWSC/CR/RDTR-42, Naval Weapons Support Center, Crane, Indiana, October 1976, available from Defense Documentation Center Cameron Station, Alexandria, Virginia, AD-A031357; in the meeting of the American Physical Society held 29 March–1 April 1976 in Atlanta, Georgia, paper FF5; in Magnetic Resonance in Colloid and Interface Science (Resing, H. A., and Wade, C. G., eds.), ACS Symposium Series No. 34 (1976), pp. 16–30, American Chemical Society, Washington, D. C.; in the 21st Annual Biophysical Society meeting, 15–18 February 1977 in New Orleans, paper F-PM-B11; and in the 24th Annual Biophysical Society meeting, 1–5 June 1980 in New Orleans, paper 813.
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Present address: Exxon Nuclear Idaho Co., Idaho Falls, Idaho 83401.