Elsevier

Developmental Biology

Volume 90, Issue 1, March 1982, Pages 198-202
Developmental Biology

Brief note
Effect of the basal diencephalon on the development of Rathke's pouch in rats: A study in combined organ cultures

https://doi.org/10.1016/0012-1606(82)90225-1Get rights and content

Abstract

Rathke's pouch of 12.5-day-old fetal rats was cultured alone or with various fetal organs. After 10 days of culture with the anterior or posterior wall of the basal diencephalon, the size of the pouch was about eight times larger than that in single culture or in combined culture with the telencephalon or liver anlage. There was no chronological difference in the appearance of immunoreactive ACTH and prolactin cells between single and combined cultures. These results suggest that fetal diencephalon promotes the growth of Rathke's pouch but has no potency to promote differentiation of the pituitary cells.

References (13)

  • M.B. Bornstein

    Reconstituted rat-tail collagen used as substrate for tissue cultures on coverslips in Maximow slides and roller tubes

    Lab. Invest

    (1958)
  • A. Chatelain et al.

    Ontogenesis of cells producing polypeptide hormones (ACTH, MSH, LPH, GH, prolactin) in the fetal hypophysis of the rat: Influence of the hypothalamus

    Cell Tissue Res

    (1979)
  • S. Daikoku et al.

    Role of hypothalamus on development of adenohypophysis: An electron microscopic study

    Neuroendocrinology

    (1973)
  • G. Fink et al.

    Ultrastructural features of the developing hypothalamo-hypophysial axis in the rat

    A correlative study

    Z. Zellforsch

    (1971)
  • P.H. Frémont et al.

    In vitro studies on the self-differentiating capacities of quail adenohypophysis epithelium

    Anat. Embryol

    (1979)
  • D.S. Gross et al.

    Developmental correlation between hypothalamic gonadotropin-releasing hormone and hypophysial luteinizing hormone

    Amer. J. Anat

    (1979)
There are more references available in the full text version of this article.

Cited by (0)

This work was supported by a grant from the Ministry of Education, Science and Culture, Japan.

View full text