Elsevier

Journal of Theoretical Biology

Volume 29, Issue 3, December 1970, Pages 471-476, IN1-IN2, 477-481
Journal of Theoretical Biology

Algebraic Reconstruction Techniques (ART) for three-dimensional electron microscopy and X-ray photography

Dedicated to Diana Gordon, artist.
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Abstract

We give a new method for direct reconstruction of three-dimensional objects from a few electron micrographs taken at angles which need not exceed a range of 60 degrees. The method works for totally asymmetric objects, and requires little computer time or storage. It is also applicable to X-ray photography, and may greatly reduce the exposure compared to current methods of body-section radiography.

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Supported in part by NASA grant NGR 33-015-016 to the Center for Theoretical Biology, the State University of New York through the Einstein chair budget of Dr C. H. Waddington, and N.S.F. Grant GJ596.

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