Elsevier

Neuropsychologia

Volume 34, Issue 11, November 1996, Pages 1097-1106
Neuropsychologia

Cerebral activations during number multiplication and comparison: a PET study

https://doi.org/10.1016/0028-3932(96)00027-9Get rights and content

Abstract

Positron emission tomography was used to examine the cerebral networks underlying number comparison and multiplication in eight normal volunteers. Cerebral blood flow was measured within anatomical regions of interest defined in each subject using magnetic resonance imaging. Three conditions were used: rest with eyes closed, mental multiplication of pairs of arabic digits and larger-smaller comparison of the same pairs. Both multiplication and comparison activated the left and right lateral occipital cortices, the left precentral gyrus, and the supplementary motor area. Beyond these common activations, multiplication activated also the left and right inferior parietal gyri, the left fusiform and lingual gyri, and the right cuneus. Relative to comparison, multiplication also yielded superior activity in the left lenticular nucleus and in Brodmann's area 8, and induced a hemispheric asymmetry in the activation of the precentral and inferior frontal gyri. Conversely, relative to multiplication, comparison yielded superior activity in the right superior temporal gyrus, the left and right middle temporal gyri, the right superior frontal gyrus, and the right inferior frontal gyrus. These results underline the role of bilateral inferior parietal regions in number processing and suggest that multiplication and comparison may rest on partially distinct networks.

References (54)

  • G.E. Alexander et al.

    Parallel organization of functionally segregated circuits linking basal ganglia and cortex

    Annual Review of Neuroscience

    (1986)
  • I. Appolonio et al.

    Functional magnetic resonance imaging (F-MRI) of calculation ability in normal volunteers

    Neurology

    (1994)
  • F. Benson et al.

    Acalculia: Acquired anarithmetica

    Cortex

    (1972)
  • A.L. Benton

    Mathematical disability and the Gerstmann syndrome

  • L. Cohen et al.

    Number words and number non-words: A case of deep dyslexia extending to arabic numerals

    Brain

    (1994)
  • L. Cohen et al.

    Number processing in pure alexia: The effect of hemispheric asymmetries and task demands

    NeuroCase

    (1995)
  • A.J. Corbett et al.

    Acalculia following a dominant-hemisphere subcortical infarct

    Archives of Neurology

    (1988)
  • S. Dehaene

    The organization of brain activations in number comparison: Event-related potentials and the additive-factors methods

    Journal of Cognitive Neuroscience

    (1995)
  • S. Dehaene

    Electrophysiological evidence for category-specific word processing in the normal human brain

    NeuroReport

    (1995)
  • S. Dehaene et al.

    Attention, automaticity, and levels of representation in number processing

    Journal of Experimental Psychology: Learning, Memory and Cognition

    (1995)
  • S. Dehaene et al.

    The mental representation of parity and numerical magnitude

    Journal of Experimental Psychology: General

    (1993)
  • S. Dehaene et al.

    Towards an anatomical and functional model of number processing

    Mathematical Cognition

    (1995)
  • J. Déjerine

    Contribution à l'étude anatomo-pathologique et clinique des différentes variétés de cécité verbale

    Mémoires de la Société de Biologie

    (1892)
  • K. den Heyer et al.

    Priming single digit numbers: Automatic spreading activation dissipates as a function of semantic distance

    American Journal of Psychology

    (1986)
  • E.M. Duncan et al.

    Isolating the effects of symbolic distance and semantic congruity in comparative judgments: An additive-factors analysis

    Memory and Cognition

    (1980)
  • P. Dupont et al.

    Different perceptual tasks performed with the same visual stimulus activation different regions of the human brain: A positron tomography study

  • M.S. Gazzaniga et al.

    Dissociation of language and cognition: A psychological profile of two disconnected right hemispheres

    Brain

    (1984)
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