The accuracy of volumetric measurement of high-grade gliomas
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Cited by (25)
Diffusion MRI outlined viable tumour volume beats GTV in intra-treatment stratification of outcome
2020, Radiotherapy and OncologyCitation Excerpt :There are several reasons for this strategy for this patient cohort as discussed in an earlier publication [2], for example that in irregularly shaped lesions a one-dimensional score is a poor surrogate for response [10]. However this remains a controversial topic and this study does not advocate the use of volumetric assessment in general since volumes may be too sensitive to delineation uncertainties [11]. The concept of a viable tumour volume is not new in radiotherapy.
Proton magnetic resonance spectroscopy predicts concurrent chemoradiotherapy response and time-to-progression in high-grade gliomas after surgery
2013, Egyptian Journal of Radiology and Nuclear MedicineCitation Excerpt :A spectrum was considered to be of poor quality when large peak line width, poor signal intensity-to-noise ratio, or obvious artifacts precluded precise quantification of some areas of the spectrum. Radiological assessment of response was carried out according to the current World Health Organization (WHO) 2000 modified MacDonald criteria change in maximal perpendicular tumor diameters 3 months after the conclusion of a therapeutic protocol as follows: (14–16) complete response (CR) is defined as complete disappearance of abnormal contrast enhancement in a patient not on steroids at the time of MRI; partial response (PR) refers to a >50% decrease in volume measure of enhancing abnormality on MRI performed more than 4 weeks after the end of therapy in a patient on a stable or decreased steroid doses; stable disease (SD) refers to no change in volume of abnormal enhancement or a change that does not meet PR or PD criteria (<50% decrease or <25% increase) in a patient on stable or decreased steroid dose; and progressive disease (PD) refers to a >25% increase in volume measure of enhancing abnormality in a patient on a stable or increased steroid dose. Patients were classified as responders (CR and PR) or non-responders (SD or PD) by comparison of post-treatment images to the pre-concurrent chemoradiotherapy (baseline) MRI images (17).
Nasopharyngeal Cancers: Which Method Should be Used to Measure these Irregularly Shaped Tumors on Cross-Sectional Imaging?
2007, International Journal of Radiation Oncology Biology PhysicsCitation Excerpt :The main limitation of this study was that the reference standard for tumor size was volume measurement on MR rather than volume of the resected specimen, because surgery is not the primary treatment for NPC. The use of volume measurements as the reference standard may be criticized because of the reported poor reproducibility of this technique when measuring poorly defined and irregularly shaped tumors (15, 16). It was for this reason that we evaluated the intraexaminer intraclass correlation coefficient in this study.
Reliability of interpretation of CT examination of the larynx in patients with glottic laryngeal carcinoma
2006, Otolaryngology - Head and Neck SurgeryValidation of a technique of computer-aided tumor volume determination
1995, Journal of Surgical Research