Elsevier

Human Pathology

Volume 12, Issue 2, February 1981, Pages 145-160
Human Pathology

The ultrastructure of neurilemoma with emphasis on antoni B tissue

https://doi.org/10.1016/S0046-8177(81)80102-5Get rights and content

Abstract

Ten neurilemomas were studied by electron microscopy. Antoni A and B tissues were identified by light microscopy on semithin sections, and the corresponding areas on adjacent ultrathin sections were studied ultrastructually. The Antoni B tissue definitely possessed features of degeneration in that the cells showed a detached basal lamina, a disrupted cell membrane, degenerated nuclei, and a significant accumulation of cytoplasmic granules and myelin figures. Added to these was intercellular edema with fibrin. The similarity of the granules in the cells of Antoni B tissue, cells of granular cell tumor, and Schwann cells in wallerian degeneration supports the conclusion that these three are related phenomena.

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Instructor in Pathology, Columbia University College of Physicians and Surgeons. Attending Pathologist, St. Luke's-Roosevelt Hospital Center, New York, New York.

Associate Professor of Pathology, Columbia University College of Physicians and Surgeons. Attending Pathologist, St. Luke's-Roosevelt Hospital Center, New York, New York.

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