Expression of glutamate transporters in the adult bovine corpus callosum

doi:10.1016/S0169-328X(99)00072-8

Molecular Brain Research

Volume 67, Issue 2, 20 April 1999, Pages 296-302

https://doi.org/10.1016/S0169-328X(99)00072-8 Get rights and content

Abstract

The presence and distribution of the glutamate transporters, EAAC1, GLAST and GLT-1, were examined in the adult bovine corpus callosum by means of Western blotting and immunohistochemistry. We found GLAST to be expressed in oligodendrocytes and in some astrocytes. GLT-1 was located throughout the processes of fibrous astrocytes. In addition, EAAC1 was present in a small population of cells that are probably adult oligodendrocyte progenitor cells.

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Acknowledgements

The authors wish to express their thanks to D.J. Fogarty for reviewing the manuscript, to Dr. J.D. Rothstein (Johns Hopkins University, Baltimore, USA) and Dr. N.C. Danbolt (Oslo University, Norway) for the gift of polyclonal antibodies to the glutamate transporters examined, and to Dr. M. Nguyen (NINDS, Bethesda, MD, USA) for providing the antiserum to nestin. This work was supported by grants from the Gobierno Vasco (97/9) and the Ministerio de Educación y Cultura (PM97-45). M. Domercq held a

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Short communicationExpression of glutamate transporters in the adult bovine corpus callosum

Abstract

Section snippets

Acknowledgements

Neuroscience

Trends Neurosci.

Neuron

Neuron

Neuroscience

Trends Neurosci.

Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance

Proc. Natl. Acad. Sci. USA

EAAC1, a high-affinity glutamate transporter, is localized to astrocytes and GABAergic neurons besides pyramidal cells in the rat cerebral cortex

Cerebral Cortex

An excitatory amino-acid transporter with properties of a ligand-gated channel

Nature

Visualization of O-2A progenitor cells in developing and adult rat optic nerve by quisqualate-stimulated cobalt uptake

J. Neurosci.

Proliferating bipotential glial progenitor cells in adult rat optic nerve

Nature

Expression of kainate-selective glutamate receptor subunits in glial cells of the adult bovine white matter

Eur. J. Neurosci.

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Short communication
Expression of glutamate transporters in the adult bovine corpus callosum