Giant cell reparative granuloma of the temporal bone: Case report and review of the literature☆,☆☆,★,★★
Section snippets
CASE REPORT
The patient is a 36-year-old woman who presented to our institution in 1990 with a feeling of fullness in her left ear. Physical examination revealed a mass bulging into the anterior aspect of the left external auditory canal. Radiographic studies demonstrated the presence of a lytic lesion in the anterior portion of the left temporal bone. A biopsy specimen of the mass was believed to be consistent with GCRG. An atticotomy and canaloplasty were performed through a left postauricular incision.
DISCUSSION
Since its first description in 1953 the term “giant cell reparative granuloma” has sparked much debate in the literature. The pathogenesis of GCRG was initially thought to be a hyperplastic reparative reaction to intraosseus hemorrhage induced by trauma. 1 However, a definite history of trauma has not been reliably elicited. 3, 15 Other theories on the pathogenesis of GCRG including infectious 7 and developmental 12 causes have been proposed, but no single theory has gained wide acceptance.
The
CONCLUSION
This was the first description of a recurrent GCRG requiring glenoid fossa reconstruction. The pathologic evaluation clearly indicated the lesion to be GCRG. When clear distinctions can be made on histologic evaluation, we advocate maintaining the current nomenclature of GCRG and GCT. Otherwise, for borderline cases the more general term “giant cell lesion” should be used with further classification as aggressive or nonaggressive based on the symptoms. It is important to recognize that although
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Cited by (30)
“Giant cell reparative tumor: An exceptional differential diagnosis for a lytic lesion of the temporal bone”
2016, NeurochirurgieCitation Excerpt :Expression of p63 has been found by some to be useful to distinguish between GCT and other non-neoplastic giant cell lesions [13]. The term “giant cell lesion” was recommended for these equivocal cases [14]. Our case shared an overlapping of all features of GCRG except the age and localization that were consistent with GCT.
Giant cell reparative granuloma of the maxillary sinus
2002, European Journal of RadiologyGiant cell reparative granuloma of the temporal bone successfully resected with preservation of hearing
2013, Journal of Laryngology and OtologyImaging Features of Craniofacial Giant Cell Granulomas: A Large Retrospective Analysis from a Tertiary Care Center
2022, American Journal of NeuroradiologyCentral giant cell granuloma of the temporal bone and temporo-mandibular-joint: a case report
2022, Frontiers of Oral and Maxillofacial MedicinePediatric giant cell reparative granuloma of the lower clivus: A case report and review of the literature
2021, Journal of Craniovertebral Junction and Spine
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From the Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, the Department of Otology and Laryngology, Harvard Medical School (Drs. Ung, Li, and McKenna), and the Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital (Dr. Keith).
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Reprint requests: Feodor Ung, MD, Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, 243 Charles St., Boston, MA 02114.
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Otolaryngol Head Neck Surgery 1998;118:525-9.
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