Journal of American Association for Pediatric Ophthalmology and Strabismus
Short ReportsIs screening for primitive neuroectodermal tumors in patients with unilateral retinoblastoma necessary?☆,☆☆
Section snippets
Case report
Leukocoria of the left eye was diagnosed in a 7-week-old girl. She had been born at term after an uneventful pregnancy and a normal vaginal delivery. Findings on ophthalmic examination revealed a stage V retinoblastoma of the left eye. No tumor was observed in the right eye. Computed tomographic (CT) findings revealed a calcified left retrolenticular lesion occupying approximately 50% of the ocular volume. The brain, specifically the pineal region, was unremarkable. No radiographic evidence was
Discussion
In 1977, Jakobiec et al1 first described the occurrence of bilateral retinoblastoma with associated pinealoblastoma. Since then, numerous reports have been made of similar cases, describing the syndrome as trilateral retinoblastoma. On the other hand, unilateral retinoblastoma with a pinealoblastoma is seldom documented in the literature. 1, 2, 3, 4, 5 In 1985, Whittle et al6 reported a nonhereditary case of unilateral retinoblastoma with concomitant pinealoblastoma in a 10-month-old boy who
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Cited by (12)
Risk factors for metastasis in retinoblastoma
2002, Survey of OphthalmologyClinical and magnetic resonance imaging features of 14 patients with trilateral retinoblastoma
2021, Quantitative Imaging in Medicine and SurgeryTrilateral retinoblastoma: A systematic review of 211 cases
2019, Neurosurgical ReviewRetinoblastoma
2013, Pediatric Retina: Second EditionTrilateral retinoblastoma with unilateral eye involvement
2013, Journal of the Pakistan Medical Association
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Supported in part by Research to Prevent Blindness and That Man May See, Inc. Submitted March 10, 1999.
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Reprint requests: Joan M. O'Brien, MD, Department of Ophthalmology, University of California, San Francisco, 10 Kirkham Street, Box 0730, San Francisco, CA 94143-0730.