Original Article
A single-institution study of predisposing factors of patients with BAVMs to flow-related aneurysm

https://doi.org/10.1016/j.jfma.2018.08.016Get rights and content
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Background and purpose

The goal of this study was to assess the potential risk factors leading to flow-related aneurysm (FA) formation in patients with brain arteriovenous malformations (BAVMs) in Taiwanese.

Methods

We recruited 890 patients with BAVMs: 72 had FA(s) and 818 did not. Several factors were assessed including patient's age, gender, BAVM volume and location, and Spetzler-Martin grade.

Results

The 890 patients with BAVM had a mean age of 30 years (range: 2–84), mean BAVM volume of 10.6 mL (range: 0.13–91.4). BAVMs were ruptured in 42% of patients. Compared to BAVM patients without FAs, the 72 patients with FAs had older age (mean 41 yrs vs 31 yrs, p < 0.001); larger average BAVM volume (39.6 mL vs 16.1 mL, p < 0.001). No statistical significance in Spetzler-Martin grades (χ2 value = 8.687 and p = 0.122) was found in terms of formation of FA. FA demonstrated similar gender distribution and BAVM location distribution (the χ2-value was 0.242 and 0.812, respectively).

Conclusion

Patients with older age and large BAVM volume are more prone to FA. Gender, BAVM location, and BAVM grade are not statistically significant predisposing factors for FA.

Keywords

Brain arteriovenous malformation
Flow-related aneurysm
Predisposing factor

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