Relating multi-sequence longitudinal intensity profiles and clinical covariates in incident multiple sclerosis lesions
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Abbreviations
CI
confidence interval
FLAIR
fluid-attenuated inversion recovery
NINDS
National Institute of Neurological Disease and Stroke
NAWM
normal-appearing white matter
MRI
magnetic resonance imaging
MS
multiple sclerosis
PC
principal component
PCA
principal component analysis
PD
proton density-weighted
RRMS
relapsing remitting MS
SPMS
secondary progressive MS
sd
standard deviation
T1
T1-weighted
T2
T2-weighted
T
Tesla
Keywords
Structural magnetic resonance imaging
Multi-sequence imaging
Longitudinal study
Multiple sclerosis
Longitudinal lesion behavior
Principal component analysis and regression
Function-on-scalar regression
Expert rater trial
Biomarker
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Copyright © 2015 The Authors. Published by Elsevier Inc.