The Risk of New Osteoporotic Vertebral Compression Fractures in the Year after Percutaneous Vertebroplasty
Section snippets
Patients
Between March 2002 and March 2004, 77 consecutive patients underwent PV of painful osteoporotic VCFs in our hospital. Eleven patients were excluded from the study. One patient died of unrelated disease within 2 months. Ten patients refused 3-month and/or 6-month follow-up MR imaging and were excluded from the study. The remaining 66 patients had 6-month follow-up MR imaging after PV and constitute the current study population. PV was performed only if conservative treatment had failed and back
RESULTS
The 66 patients treated with PV had a total of 228 preexisting VCFs with a median of three VCFs per patient (range, 1–10). Of these 228 VCFs, 102 showed bone marrow edema on MR imaging and were subsequently treated with PV in 68 sessions. Two patients were treated in two PV sessions.
There were no technical failures and there was no procedural morbidity. Injected bone cements included Simplex-P, Palacos LV-40, Osteopal V, and Osteo-Firm in 15, 28, 29, and 30 VCFs, respectively. All 66 patients
DISCUSSION
Nearly 25% of patients developed one or more new VCFs in the 1 year of follow-up after treatment of painful osteoporotic VCFs with PV. The majority of these new VCFs occurred within 3 months after PV. In the first 3 months, most new VCFs were located at adjacent levels, whereas later in follow-up, more distant levels were involved. Almost half of new VCFs were symptomatic. Presence of more than two preexisting VCFs was the only predictor in the development of new VCFs. Age, sex, presence of
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None of the authors have identified a conflict of interest.