Histological Analysis of Microbleed After Surgical Resection in a Patient With Moyamoya Disease —Case Report—

Ken-ichiro KIKUTA; Yasushi TAKAGI; Kazuhiko NOZAKI; Tsutomu OKADA; Nobuo HASHIMOTO

doi:10.2176/nmc.47.564

Case Reports

Histological Analysis of Microbleed After Surgical Resection in a Patient With Moyamoya Disease

—Case Report—

Ken-ichiro KIKUTA, Yasushi TAKAGI, Kazuhiko NOZAKI, Tsutomu OKADA, Nobuo HASHIMOTO

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Keywords: moyamoya disease, microbleeding, T₂^*-weighted magnetic resonance, histopathology, surgical resection

JOURNAL OPEN ACCESS

2007 Volume 47 Issue 12 Pages 564-567

DOI https://doi.org/10.2176/nmc.47.564

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Abstract

A 65-year-old male with moyamoya disease underwent surgical resection of a microbleed simultaneously with revascularization surgery. Histological examination identified several fragile arteries surrounding the microbleed. Microbleeds detected by T₂^*-weighted magnetic resonance imaging are considered to be a general marker of vascular vulnerability in cerebral angiopathy with a tendency to bleeding. The microbleeds observed in patients with moyamoya disease probably originate in bleeding from the fragile arteries.

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