Chondroblastoma: MR characteristics with pathologic correlation

J Comput Assist Tomogr. 1999 Sep-Oct;23(5):721-6. doi: 10.1097/00004728-199909000-00016.

Abstract

Purpose: The purpose of this study was to describe the MR findings of chondroblastoma with pathologic correlation.

Method: In 22 patients with pathologically proven chondroblastoma, MR signal characteristics were correlated with pathological findings.

Results: On T2-weighted images, 12 (55%) lesions were hyperintense with hypointense areas in 9 lesions, whereas 10 (45%) were hypointense. Therefore, 19 of 22 (86%) lesions with pathologic correlation had hypointense areas entirely (n = 10) or partly (n = 9) on T2-weighted images. On gadolinium-enhanced images, 13 (59%) lesions showed lobular enhancement and 9 (41%) showed marginal and septal enhancement. Low signal intensity on T2-weighted MR images was most strongly associated with an abundance of immature chondroid matrix, hypercellularity of the chondroblasts, calcifications, and hemosiderin on histology.

Conclusion: Chondroblastoma was found to show hypointense portions on T2-weighted images. Signal intensity on T1- and T2-weighted MR images in chondroblastoma was dependent on the amounts of histopathological components.

MeSH terms

  • Adolescent
  • Adult
  • Biopsy
  • Bone Neoplasms / diagnosis*
  • Bone Neoplasms / pathology
  • Bone and Bones / pathology
  • Chondroblastoma / diagnosis*
  • Chondroblastoma / pathology
  • Contrast Media
  • Female
  • Gadolinium DTPA
  • Humans
  • Magnetic Resonance Imaging* / instrumentation
  • Magnetic Resonance Imaging* / methods
  • Magnetic Resonance Imaging* / statistics & numerical data
  • Male
  • Retrospective Studies

Substances

  • Contrast Media
  • Gadolinium DTPA