CT-guided epidural/perineural injections in painful disorders of the lumbar spine: short- and extended-term results

Cardiovasc Intervent Radiol. 1999 Nov-Dec;22(6):493-8. doi: 10.1007/s002709900438.

Abstract

Purpose: Evaluation of short- and extended-term results of repeated epidural/perineural injections (EDT/PRT) of corticoids in painful afflictions of the lumbar spine.

Methods: Thirty-two patients who had persistent radicular or low back pain for more than 6 weeks were treated with CT-guided injection therapy. By EDT/PRT, 40 mg of triamcinolonacetonid was injected either periradicularly or by a direct intraspinal epidural method at intervals of 3 weeks. Altogether, 140 EDT/PRT were performed in 32 patients (mean 4.4, range 2-8). In nine patients partial facet joint denervation with 1-2 ml of 50% alcohol solution was combined with EDT/PRT to reduce low back pain. Before and after treatment and at follow-up (mean 9.6 months), treatment success was evaluated on a visual analog scale and by physical examination (good = >50% improvement, moderate = 20%-50%, no improvement = <20%).

Results: Short-term (end of therapy) good or moderate improvement was achieved in 91% of patients, extended-term (mean 9.6 months) in 56%. Regarding certain subgroups, those with disc herniations of the lumbar spine showed a better outcome with good or moderate improvement in 95% short-term and 69% extended-term than those with spinal stenosis who had 72% short-term and 28% long-term.

Conclusion: Results indicate that CT-guided EDT/PRT in combination with partial facet joint denervation is a safe and effective outpatient treatment.

MeSH terms

  • Anti-Inflammatory Agents / administration & dosage
  • Anti-Inflammatory Agents / therapeutic use*
  • Female
  • Follow-Up Studies
  • Humans
  • Injections, Epidural
  • Injections, Spinal
  • Intervertebral Disc Displacement / drug therapy*
  • Intervertebral Disc Displacement / physiopathology
  • Lumbar Vertebrae*
  • Male
  • Middle Aged
  • Pain Measurement
  • Spinal Stenosis / drug therapy*
  • Spinal Stenosis / physiopathology
  • Tomography, X-Ray Computed
  • Triamcinolone / administration & dosage
  • Triamcinolone / therapeutic use*

Substances

  • Anti-Inflammatory Agents
  • Triamcinolone