Long-term outcome after neurosurgically treated spinal epidural abscess following epidural analgesia

Acta Anaesthesiol Scand. 2001 Feb;45(2):233-9. doi: 10.1034/j.1399-6576.2001.450215.x.

Abstract

Background: A recent investigation demonstrated a high incidence of epidural abscess secondary to epidural catheterization and a 50% frequency of neurologic deficits. We studied short- and long-term neurologic outcome in patients operated for spinal epidural abscess after epidural analgesia.

Methods: Nineteen patients who had undergone neurosurgical decompression and drainage of a spinal epidural abscess during a 5-year period at three neurosurgical departments in East Denmark were identified by manual review of operating lists.

Results: Median epidural catheterization time was 8 days (range 3-44). Preoperatively 12 patients suffered from inferior paraparesis, one had irradiating pain from the back, and 6 patients had no neurologic deficits. Postoperatively 2 patients had recovered, but 3 other patients had deteriorated; therefore, 13 patients were discharged with paresis/plegia. Seven patients died during a median follow-up time for all patients of 41.6 months. One patient recovered completely, and one suffered from minor deficits. The remaining patients suffered from paraparesis/plegia or bladder/bowel dysfunction.

Conclusion: Overall recovery rate for patients with paresis/plegia after epidural abscess was 20%. No patients with paresis/plegia following a thoracic abscess recovered in contrast to a 50% recovery rate for patients with lumbar epidural abscess. The majority of long-term survivors had severe neurologic deficits. Abscess formation contributed to one death.

Publication types

  • Clinical Trial

MeSH terms

  • Abscess / etiology
  • Abscess / microbiology
  • Abscess / surgery*
  • Adult
  • Aged
  • Aged, 80 and over
  • Analgesia, Epidural
  • Epidural Space / microbiology
  • Epidural Space / surgery*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Paralysis / etiology
  • Retrospective Studies
  • Spinal Diseases / etiology
  • Spinal Diseases / microbiology
  • Spinal Diseases / surgery*
  • Staphylococcal Infections / etiology
  • Staphylococcal Infections / surgery
  • Treatment Outcome