Severe pulmonary hypertensive vascular disease in two newborns with aneurysmal vein of galen

N S Dahdah; H Alesseh; B Dahms; F Saker

doi:10.1007/s002460010294

Severe pulmonary hypertensive vascular disease in two newborns with aneurysmal vein of galen

Pediatr Cardiol. 2001 Nov-Dec;22(6):538-41. doi: 10.1007/s002460010294. Epub 2001 Dec 4.

Authors

N S Dahdah¹, H Alesseh, B Dahms, F Saker

Affiliation

¹ Department of Pediatrics, Division of Cardiology, MetroHealth Medical Center, Case Western Reserve University, 2500 MetroHealth Drive, Cleveland, OH 44109, USA. ndahdah@pol.net

PMID: 11894167
DOI: 10.1007/s002460010294

Abstract

Arteriovenous malformation of the vein of Galen (AVG) is a rare entity in the newborn with a high morbidity and mortality. We present two cases of fatal AVG with persistent pulmonary hypertension of the newborn and significant pulmonary hypertension documented by autopsy histopathology. The pathophysiology is reviewed and a proposed mechanism of the association between AVG and pulmonary hypertension is discussed.

Publication types

Case Reports

MeSH terms

Cerebral Veins / abnormalities*
Cerebral Veins / diagnostic imaging
Fatal Outcome
Female
Humans
Hypertension, Pulmonary / diagnostic imaging
Hypertension, Pulmonary / etiology*
Hypertension, Pulmonary / pathology*
Infant, Newborn
Intracranial Arteriovenous Malformations / complications*
Intracranial Arteriovenous Malformations / diagnostic imaging
Intracranial Arteriovenous Malformations / pathology
Ultrasonography, Prenatal