MRI and diffusion MRI in nonparaneoplastic limbic encephalitis

Comput Med Imaging Graph. 2002 Sep-Oct;26(5):339-42. doi: 10.1016/s0895-6111(02)00022-8.

Abstract

This paper reports an 65-year-old woman with nonparaneoplastic limbic encephalitis. On MRI and diffusion MRI, diffuse and symmetrical, bilateral high-signal lesions were evident in the medial temporal lobes. The affected areas were hyperintense on b= 1000 s/mm(2) (heavily diffusion-weighted or true diffusion) images, a pattern similar to cytotoxic edema. However, apparent diffusion coefficient (ADC) values read directly from corresponding ADC maps at each temporal lobe were within normal limits: 0.96 and 0.97 x 10 x (-3) mm(2)/s, respectively, excluding cytotoxic edema. The changes were shown to be resolved on a 9-month follow-up MRI.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Brain / pathology*
  • Diffusion Magnetic Resonance Imaging
  • Female
  • Humans
  • Limbic Encephalitis / diagnosis*
  • Magnetic Resonance Imaging*